ArticleSurgery today2025
Pleurodesis using 50% glucose solution for air leak after pulmonary resection: a multi-center retrospective study.
Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Effectiveness of free pericardial fat pad reinforcement for air leak control in pulmonary lobectomy.General thoracic and cardiovascular surgery · 2026Article
- 3D bioprinted coverage-type lung patch for postoperative wound sealing and prevention of pulmonary air leakage.Nanoscale advances · 2026Article
- Postoperative pleurodesis using OK-432 for pulmonary air leak in lung cancer patients with idiopathic interstitial pneumonia: A retrospective study.Surgery today · 2026Article
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Authors and funding
9 authors.
Funding
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Abstract
purposeTo assess the usefulness of and predictive factors for pleurodesis using 50% glucose solution to treat air leak after pulmonary resection.
methodsThe subjects of this retrospective study were 70 patients from three Japanese institutions, who were treated with 50% glucose solution for postoperative air leak between April, 2015 and March, 2023. Air leak was monitored using a digital drainage system. We analyzed the patient characteristics, surgical details, and outcomes. Successful pleurodesis was defined as control of the air leak within two attempts and no recurrence within 1 month after drain removal. Predictors of success were identified using multivariable logistic regression.
resultsPleurodesis with 50% glucose solution treated air leak successfully in 58 patients (83%), with a median time from resection to pleurodesis of 4 days. Air leak control was achieved within 2 days in 93% of these patients. Air leak volume < 300 mL/min before pleurodesis and an air space rate < 10% calculated on chest radiograph were independent predictors of success. The success rate for patients with both or none of these factors was 97% and 29%, respectively. No life-threatening complications were observed.
conclusionsPleurodesis using 50% glucose solution could be useful for managing postoperative air leak, especially in patients with an air leak volume < 300 mL/min and an air space rate < 10%.
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