Evidence map›Paper›PMID 40285683›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Photocatalytic Bilateral Disulfuration of Thioethers Toward α-Sulfide Disulfides With Antibacterial Activity.

Qingqiang Tian, Chuxia Wang, Bingrui Liu, Xiangwei Wu, Yahui Li

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qingqiang TianAnhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, Anhui Agricultural University, Hefei, 230036, China.
Chuxia WangAnhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, Anhui Agricultural University, Hefei, 230036, China.
Bingrui LiuAnhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, Anhui Agricultural University, Hefei, 230036, China.
Xiangwei WuAnhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, Anhui Agricultural University, Hefei, 230036, China.
Yahui LiAnhui Provincial Key Laboratory of Hazardous Factors and Risk Control of Agri-food Quality Safety, Anhui Agricultural University, Hefei, 230036, China.ORCID https://orcid.org/0000-0002-1980-1751

Funding

Excellent Youth Program of Anhui Province 2022AH030095National Key R&D Program of China 2021YFD1700100National Natural Science Foundation of China 22101005
6 · The paper itself

Abstract

α-Sulfide disulfides represent valuable motifs in organic and pharmaceutical chemistry. However, the limited availability of synthetic approaches for α-sulfide disulfides has impeded progress in this field. In this study, a photocatalytic approach to synthesizing modifiable α-sulfide disulfides is presented using accessible sulfides and a bilateral disulfurating reagent. The reaction proceeds under mild conditions and demonstrates broad substrate compatibility, accommodating both aromatic and aliphatic sulfides. Moreover, the synthesized α-sulfide disulfides display robust reactivity in subsequent transformations with different electrophiles. Notably, this protocol can also be applied to the modification of polymer matrices. Bioassays further reveal that certain target compounds exhibit significant antibacterial activity against plant pathogens, such as Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas oryzae pathovar oryzicola (Xoc), and Dickeya zeae (D. zeae).

Indexed as

Anti-Bacterial AgentsDisulfidesSulfidesCatalysisXanthomonasAnti-Bacterial AgentsDisulfidesSulfidesantibacterial activitybilateral disulfurating reagentphotocatalysisthioether C(sp3)−H bond polysulfidationα−sulfide disulfides

Identifiers

PMID40285683
PMCPMC12279184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.