Association Between Antioxidant Capacity and Vascular Hemodynamics in Premenopausal Women Following Exercise Training.

Oxidative stress plays a role in vascular dysfunction and cardiometabolic health. The purpose of this study was to assess the effects of aerobic exercise training on antioxidant capacity (ferric reducing ability of plasma/FRAP) and hemodynamic measures: systolic blood pressure (∆SBP), diastolic blood pressure (∆DBP), mean arterial blood pressure (∆MAP), large arterial elasticity index (∆LAEI), and small arterial elasticity index (∆SAEI) in a cohort of healthy women. This was a secondary data analysis of a study designed to evaluate cardiometabolic outcomes. Participants performed supervised aerobic exercise 3 times/week on a stationary cycle ergometer. FRAP and hemodynamic measures were measured baseline and post-training. The analysis included 15 African American and 14 Caucasian women aged 32.2 ± 5.5 years. No significant changes were observed for FRAP or hemodynamic measures. However, significant negative correlations between ∆FRAP and ∆SBP, ∆DBP, and MAP, as well as a positive correlation with ∆SAEI and ∆LAEI were observed. ∆SBP, ∆DBP, and ∆MAP were each modeled with three multiple regression models: (1) ∆FRAP, ∆SAEI, and ∆LAEI as independent variables. All models had significant R