Evidence map›Paper›PMID 40285493›Full record

ArticleInternational health2025

Assessing trachoma elimination progress in districts with persistent trachoma, Western Province, Zambia.

Consity Mwale, Chileshe Mboni, Ngonda Saasa, Chummy S Sikasunge, Chisanga Chelu, Tina Chisenga, Lubasi Sundano, Namasiku Siyumbwa Kunda, Phyllis M Moonga, Kaluba Lombe and 11 more

Abstract read
In one paragraph

Article in International health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Consity MwaleKitwe Teaching Eye Hospital, Administration Department, Kitwe 10101, Zambia.ORCID 0000-0001-9555-2227
Chileshe MboniKitwe Teaching Eye Hospital, Administration Department, Kitwe 10101, Zambia.
Ngonda SaasaDepartments of Disease Control and Paraclinical Studies, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, Lusaka 10101, Zambia.
Chummy S SikasungeDepartments of Disease Control and Paraclinical Studies, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, Lusaka 10101, Zambia.
Chisanga CheluMansa General Hospital, Administration Department, Mansa 10101, Zambia.
Tina ChisengaMinistry of Health, Directorates of Public Health and Clinical Care, Lusaka 10101, Zambia.
Lubasi SundanoMinistry of Health, Directorates of Public Health and Clinical Care, Lusaka 10101, Zambia.
Namasiku Siyumbwa KundaMinistry of Health, Directorates of Public Health and Clinical Care, Lusaka 10101, Zambia.
Phyllis M MoongaMinistry of Health, Directorates of Public Health and Clinical Care, Lusaka 10101, Zambia.
Kaluba LombeSightsavers, Lusaka 10101, Zambia.
Tabonga NaluondeLions Aid Zambia, Lusaka 10101, Zambia.
Sarah BoydInternational Trachoma Initiative, The Task Force for Global Health, 330 West Ponce de Leon Ave, Decatur, GA 30030, USA.
Ana BakhtiariInternational Trachoma Initiative, The Task Force for Global Health, 330 West Ponce de Leon Ave, Decatur, GA 30030, USA.
Cristina JimenezNeglected Tropical Diseases Department, Sightsavers, Haywards Heath, RH16 3BW, UK.
Emma M Harding-EschClinical Research Department, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Michael DejeneNeglected Tropical Diseases Department, Sightsavers, Addis Ababa 495, 1110, Ethiopia.
Freddie MasaningaWorld Health Organization, Lusaka 10101, Zambia.
Nathan N BakyaitaWorld Health Organization, Lusaka 10101, Zambia.
Davison KwendakwemaBeverly Eye and Dental Clinic, Ndola 10101, Zambia.
Anthony W SolomonGlobal Neglected Tropical Diseases Programme, World Health Organization, Geneva, 1211, Switzerland.
Kangwa I M MumaUniversity Teaching Hospitals-Eye Hospital, Clinical Care, Private Bag, RW 1X, 10101, Lusaka  Zambia.

Funding

Ministry of Health, LusakaUnited States Agency for International DevelopmentWorld Health Organization 001
6 · The paper itself

Abstract

backgroundTrachoma is a public health problem in Zambia. We aimed to estimate the prevalence of trachomatous inflammation-follicular (TF) in 1-9-y-olds and of trachomatous trichiasis (TT) in ≥15-y-olds after the implementation of trachoma elimination interventions to determine if the trachoma elimination thresholds had been achieved: <5% for TF in 1-9-y-olds and <0.2% TT for ≥15-y-olds.

methodsTwo rounds of impact prevalence surveys in two evaluation units (EUs) comprising four districts of Western Province were conducted; the first in 2018, the second in 2023. All individuals aged ≥1 year from 30 households of 24 clusters in each EU were examined for trachoma. Data were captured electronically.

resultsIn 2018, TF prevalence in 1-9-y-olds was 13.9% in Kalabo/Sikongo and 17.9% in Shang'ombo/Sioma. Following further interventions, TF prevalence among 1-9-y-olds in 2023 was 7.7% and 12.5%, respectively. TT prevalences in ≥15-y-olds were 0.10% and 0.79% in 2018, and 0.4% and 0.2% in 2023, respectively.

conclusionsThese EUs did not attain trachoma elimination thresholds as a public health problem. They fulfilled the WHO definition for persistent trachoma. Therefore, they warrant further investigation, including collection of Chlamydia trachomatis infection data, to inform future programmatic decision-making. Further TT surgical services are also needed.

Indexed as

Disease EradicationTrachomaTrichiasisAdolescentAdultChildChild, PreschoolChlamydia trachomatisFemaleHumansInfantMaleMiddle AgedPrevalenceYoung AdultZambiaimpact surveymass drug administrationpersistenceSAFE strategytrachomatrichiasis

Identifiers

PMID40285493
PMCPMC12585540

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.