Evidence map›Paper›PMID 40285462›Full record

ArticlePhysiological reports2025

Differential effects of female aging on sympathetic blood pressure regulation at rest and during stress in humans.

Christin Domeier, Thomas G Bissen, Joseph D Vondrasek, Matthew C Babcock, Austin T Robinson, Joseph C Watso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christin DomeierCardiovascular and Applied Physiology Laboratory, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0000-0002-3062-5584
Thomas G BissenCardiovascular and Applied Physiology Laboratory, Florida State University, Tallahassee, Florida, USA.
Joseph D VondrasekCardiovascular and Applied Physiology Laboratory, Florida State University, Tallahassee, Florida, USA.
Matthew C BabcockDepartment of Medicine, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, USA.
Austin T RobinsonNeurovascular Physiology Laboratory, Indiana University, Bloomington, Indiana, USA.
Joseph C WatsoCardiovascular and Applied Physiology Laboratory, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0000-0001-7840-0643

Funding

Racial Differences in Serum Sodium and Blood Pressure RegulationK01HL147998 · NHLBI · TRUSTEES OF INDIANA UNIVERSITY · PI ROBINSON, AUSTIN TYLER · 2019 to 2023
$705k
Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults with ObesityK01HL160772 · NHLBI · FLORIDA STATE UNIVERSITY · PI Joseph Watso · 2022 to 2026
$693k
Neural and Renal Contributions to Hypertension with Androgen Deprivation TherapyK01HL164978 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew C Babcock · 2023 to 2026
$665k
Dietary Ketone Supplementation as a Novel Strategy to Attenuate the Adverse Vascular and Renal Consequences of High Dietary Salt in Older AdultsR21AG087524 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI ROBINSON, AUSTIN TYLER · 2024 to 2025
$454k
American Heart Association (AHA) 23CDA1037938Florida State University (FSU)HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) K01HL147998HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) K01HL160772HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) K01HL164978NHLBI NIH HHS K01 HL147998NHLBI NIH HHS K01 HL160772NHLBI NIH HHS L30 HL154189NHLBI NIH HHS L30 HL154374NIA NIH HHS R21 AG087524
6 · The paper itself

Abstract

Older female (OF) adults exhibit blunted resting sympathetic blood pressure (BP) transduction compared with young female (YF) adults, affecting BP regulation. However, studies often lack control over health factors like body composition or habitual physical activity. Therefore, we compared resting sympathetic BP transduction and neurovascular responses during cold pressor test (CPT) and end-expiratory apnea between YF (n = 12) and OF (n = 9) matched for several health factors. We measured beat-to-beat hemodynamics and muscle sympathetic nerve activity (MSNA). OF exhibited higher resting supine BP and MSNA (p

Indexed as

AgingBlood PressureRestSympathetic Nervous SystemAdultAgedApneaFemaleHumansMiddle AgedMuscle, SkeletalYoung Adultagingapneacardiovascularcold pressor testsympathetic transduction

Identifiers

PMID40285462
PMCPMC12032447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.