ArticleSubstance use & misuse2025
A Mixed-Methods Study of Motives for Benzodiazepine Misuse Among Adults Receiving Substance Use Disorder Treatment.
Article in Substance use & misuse, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Emergence of Novel Benzodiazepines in Australia, Evidence, Alerts, Clinical Management and Harm Reduction-A Narrative Review.Drug and alcohol review · 2026Review
- Preclinical evidence for a novel pharmacotherapeutic approach for treating benzodiazepine addiction.Translational psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundBenzodiazepine misuse is common among individuals with substance use disorders (SUDs) and is associated with poorer clinical outcomes. As benzodiazepines have heterogeneous effects, standard measures of substance use motives may overlook key reasons for misuse. Understanding motives better can inform intervention development.
objectivesOur overarching objective was to characterize motives for benzodiazepine misuse among individuals with SUDs and develop a preliminary measure of these motives.
methodsWe used a two-study, mixed methods design. Participants were recruited from a continuum of SUD treatment programs at a private psychiatric hospital. Study 1 participants (
resultsQualitative analysis from Study 1 revealed six themes reflecting motives subtypes for benzodiazepine misuse, including (1) coping, (2) other substance (i.e., non-benzodiazepine) related, (3) sleep, (4) recreational, (5) benzodiazepine withdrawal and habit, and (6) social contextual. Results from Study 2 further supported the misuse of benzodiazepines to cope with negative affect, modulate the effects of non-benzodiazepine drugs, and improve sleep.
conclusionThis study revealed a broad range of benzodiazepine misuse motives in adults with SUDs, spanning misuse for drug-indicated reasons (e.g., anxiety, sleep), compensatory or synergistic effects with other drugs, physiological dependence, and recreational and social reasons. Treatments for benzodiazepine misuse may need to target multiple, varied motivators for misuse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.