Evidence map›Paper›PMID 40285398›Full record

SynthesisJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Impact of Intraoperative Interventions on Hypocalcemia Post-Total Thyroidectomy: A Meta-Analysis.

Hao-Wei Hsu, Sheng-Hsin Huang, Shao Huai Lee, Shih-Tsang Lin, Mingchih Chen, Ru-Yung Yang, Shyh-Dye Lee, Jeng-Wen Chen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao-Wei HsuDepartment of Education, Taipei Veterans General Hospital, Taipei, Taiwan.
Sheng-Hsin HuangDepartment of Education, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan.
Shao Huai LeeDepartment of Oral Hygiene and Healthcare, Cardinal Tien Junior College of Healthcare and Management, New Taipei City, Taiwan.ORCID 0000-0003-2889-1995
Shih-Tsang LinDepartment of Otolaryngology-Head and Neck Surgery, Cardinal Tien Hospital and Fu Jen Catholic University, New Taipei City, Taiwan.ORCID 0000-0003-2996-4922
Mingchih ChenDepartment of Medical Management, Graduate Institute of Business Administration, Fu Jen Catholic University, New Taipei City, Taiwan.
Ru-Yung YangDepartment of Medical Management, Graduate Institute of Business Administration, Fu Jen Catholic University, New Taipei City, Taiwan.ORCID 0000-0001-5747-6753
Shyh-Dye LeeSchool of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.
Jeng-Wen ChenDepartment of Otolaryngology-Head and Neck Surgery, Cardinal Tien Hospital and Fu Jen Catholic University, New Taipei City, Taiwan.ORCID 0000-0003-3635-4815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ImportancePostoperative hypocalcemia following total thyroidectomy (TT) can significantly affect patients' quality of life. However, the most effective intraoperative interventions to mitigate this risk remain uncertain.ObjectiveTo assess the efficacy of parathyroid gland autotransplantation (PTA), near-infrared autofluorescence (NIRAF), and indocyanine green angiography (ICGA) in reducing postoperative hypocalcemia risk after TT.DesignMeta-analysis.SettingThis meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, utilizing data from PubMed, Embase, and the Cochrane Library, with searches conducted through February 2024.ParticipantsPatients undergoing TT with or without intraoperative interventions of PTA, NIRAF, ICGA, or a combined approach.InterventionsPTA, NIRAF, ICGA, or a combination of these methods.Main Outcome MeasuresIncidence of postoperative transient and permanent hypocalcemia.ResultsFrom 582 identified records, 32 studies, including 13,299 TT patients (6386 with benign and 6913 with malignant conditions), met the inclusion criteria. PTA was associated with a higher incidence of transient postoperative hypocalcemia (OR = 1.98; 95% CI: 1.42-2.77;

Indexed as

HypocalcemiaIntraoperative CareParathyroid GlandsPostoperative ComplicationsThyroidectomyHumansOptical ImagingTransplantation, Autologoushypocalcemiaindocyanine green angiographynear-infrared autofluorescenceparathyroid gland autotransplantationthyroidectomy

Identifiers

PMID40285398
PMCPMC12035127

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.