Evidence map›Paper›PMID 40284986›Full record

ArticleViruses2025

Detection and Molecular Characterization of Novel Porcine Parvovirus 8 Strains in China.

Wei Chen, Yanqing Hu, Yan Qin, Yuying Li, Xinyu Zhang, Haixin Huang, Mengjia Liu, Yuping Zheng, Xuelian Lu, Qiaoqiong Wang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wei ChenWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.ORCID 0009-0004-1976-4462
Yanqing HuWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Yan QinWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Yuying LiWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Xinyu ZhangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Haixin HuangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Mengjia LiuWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Yuping ZhengWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Xuelian LuWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Qiaoqiong WangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Jianuo YangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Liting KangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Lulu XieWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Baopeng ZhaoWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Tian LanWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.
Wenchao SunWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.ORCID 0000-0002-8845-6242

Funding

Wenzhou Basic Agricultural Science and Technology Project Grant Numbers N2023002 and Y20220136
6 · The paper itself

Abstract

Porcine parvovirus 8 (PPV8), the most recently discovered PPV genotype, was first reported in pigs in Guangdong, China, in 2021. In this study, we assessed 69 lung tissue samples collected from animals with high fever or respiratory syndrome on pig farms in Guangxi in 2018. Five nearly full-length genome sequences were characterized and analyzed. The percentage of PPV8-positive samples was 13.04% (9/69), and five complete PPV8 sequences were obtained, which were designated PPV8-A, PPV-B, PPV8-G, PPV8-H, and PPV8-I. The genomic sequence homology among the five PPV8 strains and other PPVs was 25.91-98.84%, with the closest genetic relationship to PPV8-GDJM2021 (98.84%), followed by PPV1 (44.64%). For the NS1 protein, phylogenetic analysis revealed that the identified PPV8-I was closely related to PPV8-GDJM2021 and that PPV8-A was closely related to PPV8-H, whereas PPV8-B and PPV8-G were more distantly related to the other PPV8 strains. For the VP1 protein, phylogenetic analysis revealed a close correlation between PPV8-H and PPV8-GMJM2021, whereas PPV8-A, PPV8-B, PPV8-G, and PPV8-I were more distantly related. In conclusion, five nearly full-length sequences were amplified, and the molecular characteristics of PPV8 were analyzed. These findings improve our understanding of the PPV8 genome.

Indexed as

Parvoviridae InfectionsParvovirus, PorcineSwine DiseasesAnimalsChinaGenome, ViralGenotypePhylogenySwinegenomehomologyparvovirusphylogenetic analysisPPV8

Identifiers

PMID40284986
PMCPMC12031171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.