Evidence map›Paper›PMID 40284944›Full record

ArticleViruses2025

Expression Profile of Human Cytomegalovirus

Giovana W C Almeida, Martha T Oliveira, Isabella G L Martines, Giuliano C Fiori, Michael M Nevels, Ian J Groves, John Sinclair, José Medina-Pestana, Rayra Sampaio da Silva, Monica Nakamura and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giovana W C AlmeidaCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, SP, Brazil.
Martha T OliveiraCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, SP, Brazil.ORCID 0000-0002-4778-459X
Isabella G L MartinesCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, SP, Brazil.
Giuliano C FioriCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, SP, Brazil.
Michael M NevelsSchool of Biology, University of St. Andrews, St. Andrews KY16 9ST, UK.ORCID 0000-0002-7115-407X
Ian J GrovesMolecular Medicine, Cleveland Clinic, Cleveland, OH 44106, USA.ORCID 0000-0001-8882-6701
John SinclairDepartment of Medicine, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0002-2616-9571
José Medina-PestanaHospital do Rim, Fundação Oswaldo Ramos, Vila Clementino 04038-002, SP, Brazil.ORCID 0000-0002-0750-7360
Rayra Sampaio da SilvaHospital do Rim, Fundação Oswaldo Ramos, Vila Clementino 04038-002, SP, Brazil.
Monica NakamuraHospital do Rim, Fundação Oswaldo Ramos, Vila Clementino 04038-002, SP, Brazil.ORCID 0000-0003-4814-4452
Lucio Requião-MouraHospital do Rim, Fundação Oswaldo Ramos, Vila Clementino 04038-002, SP, Brazil.ORCID 0000-0001-8751-9048
Emma PooleDepartment of Pathology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3904-6121
Maria C Carlan da SilvaCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, SP, Brazil.ORCID 0000-0003-4081-8272

Funding

British Medical Research Program Grant MR/S00081X/1Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/08527-1
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) is a high-risk pathogen in immunocompromised individuals, especially in transplant recipients. HCMV viremia must be monitored, and frequently, patients are treated with antiviral agents. HCMV has a variety of strategies to modulate host antiviral responses, and one important player is a viral homolog of the cellular interleukin-10 (cIL-10). The viral

Indexed as

CytomegalovirusCytomegalovirus InfectionsInterleukin-10Kidney TransplantationViral ProteinsCells, CulturedFemaleGene Expression ProfilingHumansLeukocytes, MononuclearMaleMiddle AgedTransplant RecipientsVirus LatencyVirus ReplicationIL10 protein, humanInterleukin-10Viral ProteinsHCMV IL-10HCMV latent infectionHCMV lytic infectionhuman cytomegalovirus (HCMV)kidney transplantUL111A transcripts

Identifiers

PMID40284944
PMCPMC12031159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.