ArticleViruses2025
Isolation, Identification, and Pathogenicity of an Avian Reovirus Epidemic Strain in Xinjiang, China.
Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Article
- Review
- Novel multigene molecular characterization of avian reovirus strains and associated embryonic pathogenicity.Journal of virology · 2026Article
- Heterologous expression, immunogenic evaluation, and subunit vaccine potential of the σC protein from the Xinjiang avian reovirus (ARV) strain xj-1.1.Poultry science · 2026Article
- Development of a Highly Sensitive ELISA for Detecting Antibodies Against a Novel Variant Avian Reovirus Based on Dual σC and σB Antigens.Animals : an open access journal from MDPI · 2026Article
- Reovirus Infections in Broiler Chickens: A Narrative Review.Veterinary sciences · 2025Review
- Constellation-based classification of avian reovirus in turkeys reveals shared virus origins among different meat-type farms.Frontiers in veterinary science · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
To investigate the prevalence and pathogenic characteristics of avian reovirus (ARV) in the Xinjiang region of China, this study collected suspected joint tissue samples from broiler farms across different areas of the Taikun Group. The samples were subjected to virus isolation, RT-PCR analysis, sequence analysis, in vitro replication assays, and pathogenicity assessments in specific pathogen-free (SPF) chicken embryos and chickens. The results revealed the isolation of a chicken-derived ARV epidemic strain, designated as ARV xj-1.1. The virus-induced cytopathic effects (CPEs) in LMH cells and the time required to observe CPEs significantly decreased with serial blind passages. Pathogenicity testing demonstrated that ARV xj-1.1 is highly virulent to SPF chicken embryos and chickens. Inoculation of SPF chicken embryos resulted in a 100% mortality rate, while inoculation of 1-day-old SPF chicks caused significant swelling of the footpads. In conclusion, this study successfully isolated an epidemic strain of avian reovirus, providing a valuable theoretical basis for understanding the genetic evolution and epidemiology of ARV variants in the Xinjiang region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.