Evidence map›Paper›PMID 40284930›Full record

ArticleViruses2025

Evaluation of SARS-CoV-2 Seroprevalence and Variant Distribution During the Delta-Omicron Transmission Waves in Greater Accra, Ghana, 2021.

Elvis Suatey Lomotey, Jewelna Akorli, Millicent Opoku, Daniel Adjei Odumang, Kojo Nketia, Emmanuel Frimpong Gyekye, Kojo Mensah Sedzro, Nana Efua Andoh, Yvonne Ashong, Benjamin Abuaku and 2 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elvis Suatey LomoteyDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0002-3577-3375
Jewelna AkorliDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0002-3972-0860
Millicent OpokuDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.
Daniel Adjei OdumangDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0001-7261-2063
Kojo NketiaDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0009-0006-8009-5450
Emmanuel Frimpong GyekyeDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0002-7778-6748
Kojo Mensah SedzroDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.
Nana Efua AndohDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.
Yvonne AshongDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0003-3305-223X
Benjamin AbuakuDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0002-1840-6979
Kwadwo A KoramDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.
Irene Owusu DonkorDepartment of Epidemiology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra P.O. Box LG 581, Ghana.ORCID 0000-0002-8523-955X

Funding

African Academy of Sciences SARSCov2-4-20-004Bill and Melinda Gates Foundation ID INV-024130World Health Organization 2021/1166179-0
6 · The paper itself

Abstract

A significant proportion of SARS-CoV-2 infections in Africa were identified as asymptomatic. With the surge of the Omicron variant, asymptomatic participants in epidemiological surveys were key to accurately estimating seroprevalence and true infections in the population. This study assessed seroprevalence, active infections, and circulating variants in Accra, Ghana, during the Omicron wave. Secondary objectives included assessing the association between seroprevalence and sociodemographic factors, vaccination, and adherence to recommended SARS-CoV-2 prevention and control measures. We conducted a cross-sectional survey in Greater Accra in December 2021 using a standardized questionnaire. Serum and naso-oropharyngeal swab samples were collected from 1027 individuals aged ≥ 5 years for the estimation of total antibodies and detection of infection. The study found an overall seroprevalence of 86.8% [95% CI: 84.53-88.77]. PCR test positivity of SARS-CoV-2 was 10%, with the Omicron and Delta variants accounting for 44.1% and 8.8% of infections, respectively. Vaccination (cOR = 10.5, 95% CI: 4.97-26.9,

Indexed as

COVID-19SARS-CoV-2AdolescentAdultAgedAntibodies, ViralChildChild, PreschoolCross-Sectional StudiesFemaleGhanaHumansMaleMiddle AgedSeroepidemiologic StudiesVaccinationAntibodies, ViralDeltainfectionOmicronSARS-CoV-2sensitivityseroprevalence

Identifiers

PMID40284930
PMCPMC12031444

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.