Evidence map›Paper›PMID 40284874›Full record

ArticleVeterinary sciences2025

Meta-Analysis of Dietary Interventions for Enteric Methane Mitigation in Ruminants Through Methodological Advancements and Implementation Pathways.

Rayudika Aprilia Patindra Purba, Papungkorn Sangsawad

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rayudika Aprilia Patindra PurbaPostharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0003-4672-1455
Papungkorn SangsawadPostharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0003-2420-8634

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis systematically evaluates the efficacy of dietary interventions for mitigating enteric methane production in ruminants through the application of advanced statistical methodologies. A comprehensive dataset comprising 119 peer-reviewed publications (2000-2024) was analyzed using robust variance estimation, multilevel modeling, and network meta-analysis to quantify intervention efficacy and identify moderating factors while properly accounting for within-study dependencies. The results demonstrate a clear efficacy hierarchy of macroalgae (51.0% reduction [95% CI: 37.0-63.0%]), 3-nitrooxypropanol (3-NOP; 30.6% [95% CI: 22.0-45.0%]), nitrate (16.0% [95% CI: 6.0-26.0%]), oils (14.7% [95% CI: 5.0-24.0%]), and phytochemicals (13.5% [95% CI: 4.0-22.0%]). The meta-regression analyses identified significant dose-response relationships for macroalgae (coefficient = -0.212,

Indexed as

3-nitrooxypropanolclimate change mitigationenteric methanegreenhouse gas emissionsimplementation sciencemacroalgaemeta-analysisrobust variance estimationruminant nutritionsustainable livestock production

Identifiers

PMID40284874
PMCPMC12031153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.