Evidence map›Paper›PMID 40284848›Full record

ArticleVeterinary sciences2025

Diagnostic and Prognostic Value of Blood Ratios in Canine Splenic Hemangiosarcoma: A Multicentric Observational Study.

Ana M Marques, Gonçalo Petrucci, Hugo Gregório, Luís Lobo, Joaquim Henriques, Ana C Figueira, Hugo Vilhena, Carla Marrinhas, Felisbina L Queiroga

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana M MarquesDepartment of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
Gonçalo PetrucciVasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Escola Universitária Vasco da Gama (EUVG), Av. José R Sousa Fernandes, 297, 3020-210 Coimbra, Portugal.ORCID 0000-0003-1751-2419
Hugo GregórioAnimal and Veterinary Research Center (CECAV), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.ORCID 0000-0003-4346-2259
Luís LoboOneVet Group, Hospital Veterinário do Porto, Rua Palmeiras 19, 4150-562, Porto, Portugal.
Joaquim HenriquesAnicura Atlântico, Hospital Veterinário, Rua Quintino António Gomes 12, 2640-402 Mafra, Portugal.ORCID 0000-0002-2293-2277
Ana C FigueiraVasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Escola Universitária Vasco da Gama (EUVG), Av. José R Sousa Fernandes, 297, 3020-210 Coimbra, Portugal.ORCID 0000-0002-7770-6752
Hugo VilhenaVasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Escola Universitária Vasco da Gama (EUVG), Av. José R Sousa Fernandes, 297, 3020-210 Coimbra, Portugal.ORCID 0000-0003-3976-1619
Carla MarrinhasVasco da Gama Research Centre (CIVG), Department of Veterinary Sciences, Escola Universitária Vasco da Gama (EUVG), Av. José R Sousa Fernandes, 297, 3020-210 Coimbra, Portugal.
Felisbina L QueirogaDepartment of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.ORCID 0000-0001-6130-8381

Funding

Fundação para a Ciência e Tecnologia UIDB/CVT/00772/2020
6 · The paper itself

Abstract

Peripheral complete blood cell count (CBC) and blood ratios, including neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-red blood cell ratio (NRR), and platelet-to-lymphocyte ratio (PLR), have been used in the diagnosis and prognosis of several cancers; however, their relevance in canine splenic hemangiosarcoma (HSA) remains to be investigated. This study investigated whether CBC, NLR, NRR, and PLR could be diagnostic and prognostic biomarkers in dogs with splenic HSA. Analyzing medical records of 154 dogs undergoing splenectomy from 2018 to 2022, we found that dogs diagnosed with splenic HSA (n = 63) had significantly higher neutrophil counts (14.9 ± 9.7 vs. 12.6 ± 9.6;

Indexed as

blood cell countcancerdogNLRNRRPLRsplenic tumors’

Identifiers

PMID40284848
PMCPMC12031375

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.