Evidence map›Paper›PMID 40284798›Full record

ArticleVeterinary sciences2025

An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (

Guangzheng Liu, Yixiu Peng, Zeyu Li, Xilin Zhu, Hongyan Sun, Guohong Chen, Qisheng Zuo, Yingjie Niu, Jiuzhou Song, Wei Han and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guangzheng LiuJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.ORCID 0009-0002-6162-1903
Yixiu PengJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Zeyu LiJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Xilin ZhuJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Hongyan SunJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Guohong ChenJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Qisheng ZuoJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Yingjie NiuJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0003-1829-1718
Jiuzhou SongDepartment of Animal & Avian Sciences, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0002-6973-5959
Wei HanJiangsu Institute of Poultry Sciences/Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou 225003, China.
Wanhong WeiCollege of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China.
Bichun LiJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0003-0209-0479
Kai JinJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0003-2489-2173

Funding

China Postdoctoral Science Foundation 2022M722697the "JBGS" Project of Seed Industry Revitalization in Jiangsu Province JBGS〔2021〕029The National Natural Science Foundation of China 32172718, 32202655 and 32372864
6 · The paper itself

Abstract

Aromatase, a crucial enzyme for estrogen synthesis, plays a vital role in gender determination and differentiation. This study aimed to establish an inducible knockout model of the chicken

Indexed as

chickensCRISPR/Cas9gender controlgene knockoutTet-on

Identifiers

PMID40284798
PMCPMC12031565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.