Evidence map›Paper›PMID 40284703›Full record

ArticleMicroorganisms2025

Periodontal Health in Individuals Living with HIV: An Exploratory and Descriptive Molecular Approach of Microbial Interspecific and Intraspecific Diversity in Brazilian Patients.

Patricia N Olivares Ponce, Lana Bitencourt Chaves, Daiana de Souza Perce-da-Silva, Ana Luiza Carneiro-Alencar, Cinthia Magalhães Rodolphi, Isabela Ferreira Soares, Rodrigo Nunes Rodrigues-da-Silva, Ana Caroline Alves-da-Silva, Fabio Vidal Marques, Rafael Vidal Peres and 5 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Patricia N Olivares PonceImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Lana Bitencourt ChavesImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Daiana de Souza Perce-da-SilvaClinical Immunology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Ana Luiza Carneiro-AlencarImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Cinthia Magalhães RodolphiImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Isabela Ferreira SoaresImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.
Rodrigo Nunes Rodrigues-da-SilvaLaboratory of Hantaviroses and Rickettsioses, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0002-9772-849X
Ana Caroline Alves-da-SilvaPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.
Fabio Vidal MarquesPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.
Rafael Vidal PeresPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.
Dennis de Carvalho FerreiraPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.
Rodrigo Carvalho de SouzaPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.
Cristiane GonçalvesPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.ORCID 0000-0001-7889-6765
Lucio Souza GonçalvesPostgraduate Program in Dentistry, Faculty of Dentistry, Estácio de Sá University-IDOMED, Rio de Janeiro 22640-100, RJ, Brazil.ORCID 0000-0002-4388-6310
Josué da Costa Lima-JuniorImmunoparasitology Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, RJ, Brazil.ORCID 0000-0002-5848-404X

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/210.068/2023, E26/204.328/2024, E-26/200.991/2022
6 · The paper itself

Abstract

Oral manifestations of HIV infection can be an early sign of the disease and may indicate progression to AIDS. Although antiretroviral therapies, especially highly active antiretroviral therapy (HAART), have reduced the prevalence of HIV-related oral lesions, ongoing updates in diagnosis and treatment are essential due to the extended life expectancy of individuals living with HIV. Periodontal disease is a significant concern in these patients, influenced by altered immune responses and microbial dynamics, though the mechanisms are not fully understood. This exploratory study aimed to investigate the oral microbiota and periodontal disease prevalence in HIV-positive individuals by analyzing subgingival plaque samples from 24 patients. We identified 12 bacterial species using Polymerase Chain Reaction (PCR) and amplicon sequencing. Seven species were detected, with

Indexed as

bacterial diversitygenetic diversityHIVmolecular identificationoral health

Identifiers

PMID40284703
PMCPMC12029874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.