Evidence map›Paper›PMID 40284539›Full record

ArticleMicroorganisms2025

Allogeneic Hematopoietic Stem Cell Transplantation Despite Severe

Monica Tozzi, Adele Santoni, Marta Franceschini, Margherita Malchiodi, Irene Bernareggi, Beatrice Esposito Vangone, Corrado Zuanelli Brambilla, Elisabetta Zappone, Mariapia Lenoci, Francesca Toraldo and 9 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Monica TozziCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Adele SantoniHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0009-0006-9848-645X
Marta FranceschiniHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.
Margherita MalchiodiHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.
Irene BernareggiHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.
Beatrice Esposito VangoneHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.
Corrado Zuanelli BrambillaHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-6396-2990
Elisabetta ZapponeHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-4276-0214
Mariapia LenociCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Francesca ToraldoCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Valeria Del ReCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Alice PietriniApheresis Unit, Blood Transfusion Service, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Elena MarchiniApheresis Unit, Blood Transfusion Service, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Antonella FossiRespiratory Diseases, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-5494-6147
David BennettRespiratory Diseases, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.
Elena BargagliRespiratory Diseases, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-8351-3703
Giuseppe MarottaCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Alessandro BucalossiCellular Therapy and Blood Establishment Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Monica BocchiaHematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3538-3913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solid-organ transplant patients require prolonged immunosuppression, increasing their risk of hematologic disorders. For these conditions, allogeneic hematopoietic stem cell transplantation (HSCT) is a potential treatment, but it carries significant risk of treatment-related mortality due to the high possibility of developing rare infectious complications. We report a case of a 55-years-old male with a history of bilateral lung transplantation for extrinsic allergic alveolitis in 2015, who developed acute myeloid leukemia/myelodysplastic syndrome (AML/MDS) with TP53 mutation seven years later. During induction therapy, he experienced systemic fungal infection caused by

Indexed as

acute myeloid leukemiaallogeneic hematopoietic stem cell transplantationfungal infectionFusarium solanilung transplant

Identifiers

PMID40284539
PMCPMC12029724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.