Evidence map›Paper›PMID 40284468›Full record

ArticlePharmaceutics2025

Monitoring of Nutrients, Metabolites, IgG Titer, and Cell Densities in 10 L Bioreactors Using Raman Spectroscopy and PLS Regression Models.

Morandise Rubini, Julien Boyer, Jordane Poulain, Anaïs Berger, Thomas Saillard, Julien Louet, Martin Soucé, Sylvie Roussel, Sylvain Arnould, Murielle Vergès and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Morandise RubiniCentre de Biophysique Moléculaire (UPR CNRS 4301), Département Nanomédicaments et Nanosondes, UFR de Pharmacie Philippe Maupas, Université de Tours, 31 avenue Monge, 37 000 Tours, France.ORCID 0009-0000-0109-0915
Julien BoyerOndalys, 4 Rue Georges Besse, 34 830 Clapiers, France.
Jordane PoulainOndalys, 4 Rue Georges Besse, 34 830 Clapiers, France.
Anaïs BergerBioengineering, Bio-S, Technologie Servier, 905 Route de Saran, 45 520 Gidy, France.
Thomas SaillardBioengineering, Bio-S, Technologie Servier, 905 Route de Saran, 45 520 Gidy, France.
Julien LouetIndatech-Chauvin Arnoux Group, 4 Rue George Besse, 34 830 Clapiers, France.
Martin SoucéCentre de Biophysique Moléculaire (UPR CNRS 4301), Département Nanomédicaments et Nanosondes, UFR de Pharmacie Philippe Maupas, Université de Tours, 31 avenue Monge, 37 000 Tours, France.ORCID 0000-0002-6627-9660
Sylvie RousselOndalys, 4 Rue Georges Besse, 34 830 Clapiers, France.
Sylvain ArnouldBioengineering, Bio-S, Technologie Servier, 905 Route de Saran, 45 520 Gidy, France.
Murielle VergèsBioengineering, Bio-S, Technologie Servier, 905 Route de Saran, 45 520 Gidy, France.
Fabien Chauchard-RiosIndatech-Chauvin Arnoux Group, 4 Rue George Besse, 34 830 Clapiers, France.
Igor ChourpaCentre de Biophysique Moléculaire (UPR CNRS 4301), Département Nanomédicaments et Nanosondes, UFR de Pharmacie Philippe Maupas, Université de Tours, 31 avenue Monge, 37 000 Tours, France.

Funding

BpiFrance DOS0162921/00CPER-FEDER CPER-FEDERFondation Philippe Maupas Fondation Philippe MaupasUniversity of Tours University of Tours
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bioprocess monitoringchemometric analysisCHO cell cultureIgG titer predictionpartial least squares (PLS) regressionprocess analytical technology (PAT)Raman spectroscopy

Identifiers

PMID40284468
PMCPMC12030344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.