Evidence map›Paper›PMID 40284422›Full record

ArticlePharmaceutics2025

The Clinical Utility of Precision-Guided Dosing for Adalimumab Therapy Optimization in Inflammatory Bowel Disease: A Clinical Experience Program.

Stephen B Hanauer, Esther A Torres, Patricia Aragon-Han, Jonathon C Chapman, Arun C Swaminath, Ronen Arai, Mandalina Butnariu, Thomas C Lee, Shervin Rabizadeh, Morgan Check and 14 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Stephen B HanauerSchool of Medicine, Northwestern University Feinberg, Chicago, IL 60611, USA.ORCID 0000-0002-3268-932X
Esther A TorresDepartment of Medicine, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan 00936, Puerto Rico.ORCID 0000-0002-1276-0731
Patricia Aragon-HanPrometheus Laboratories Inc., San Diego, CA 92121, USA.
Jonathon C ChapmanBaton Rouge General Medical Center-Mid City, Baton Rouge, LA 70806, USA.
Arun C SwaminathLenox Hill Hospital, New York, NY 10075, USA.
Ronen AraiGastroHealth, Coral Springs, FL 33065, USA.
Mandalina ButnariuDivision of Gastroenterology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Thomas C LeeAssociated Gastroenterologists of CNY, Camillus, NY 13031, USA.ORCID 0009-0007-7529-6431
Shervin RabizadehCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Morgan CheckCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Terrence A BarrettDivision of Digestive Disease and Nutrition, University of Kentucky Medical Center, Lexington, KY 40536, USA.
Jana G HashashMayo Clinic, Florida, Jacksonville, FL 32224, USA.ORCID 0000-0001-8305-9742
Thomas MeisterGastroenterology Associates Colorado Springs, Colorado Springs, CO 80907, USA.
Eugene F YenSchool of Medicine, Northwestern University Feinberg, Chicago, IL 60611, USA.
Jami KinnucanMayo Clinic, Florida, Jacksonville, FL 32224, USA.
Daniel J SteinDivision of Gastroenterology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
David ZiringCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Rimma ShaposhnikovUCLA Westlake Village, Thousand Oaks, CA 91362, USA.
Preetika SinhDivision of Gastroenterology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-7359-1276
Taha M QaziCleveland Clinic, Cleveland, OH 44195, USA.
Andres J YarurCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Farah MonzurStony Brook Medicine, Stony Brook, NY 11794, USA.
Thierry DervieuxPrometheus Laboratories Inc., San Diego, CA 92121, USA.
Bincy P AbrahamHouston Methodist, Houston, TX 77030, USA.ORCID 0000-0003-0308-1224

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adalimumabclearancedose optimizationinflammatory bowel diseasepharmacokineticsprecision-guided dosingprecision medicinereal-world datatherapeutic drug monitoring

Identifiers

PMID40284422
PMCPMC12030419

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.