Evidence map›Paper›PMID 40284409›Full record

ReviewPharmaceutics2025

Pharmacokinetics of Psilocybin: A Systematic Review.

Shakila Meshkat, Huda Al-Shamali, Argyrios Perivolaris, Trusha Tullu, Richard J Zeifman, Yanbo Zhang, Lisa Burback, Olga Winkler, Andrew Greenshaw, Muhammad Ishrat Husain and 6 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Contribution of the Serotonin 5-HTNeuropsychopharmacology reports · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Trip killers: Addressing a critical knowledge gap in psychedelic research.Journal of psychopharmacology (Oxford, England) · 2026
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shakila MeshkatInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Huda Al-ShamaliInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Argyrios PerivolarisInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Trusha TulluInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Richard J ZeifmanNYU Center for Psychedelic Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-3478-4483
Yanbo ZhangDepartment of Psychiatry, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-2421-157X
Lisa BurbackDepartment of Psychiatry, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0001-9591-4355
Olga WinklerDepartment of Psychiatry, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0001-7297-1250
Andrew GreenshawDepartment of Psychiatry, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-9097-900X
Muhammad Ishrat HusainDepartment of Psychiatry, University of Toronto, Toronto, ON M5S 1A1, Canada.
Amy C ReicheltDepartment of Physiology and Pharmacology, Western University, London, ON N6A 3K7, Canada.
Eric VermettenDepartment of Psychiatry, Leiden University Medical Center, 2333 ZG Leiden, The Netherlands.ORCID 0000-0003-0579-4404
Manish K JhaDepartment of Psychiatry, O'Donnell Brain Institute, UT Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-2764-2391
Rakesh JetlyInstitute of Mental Health Research, University of Ottawa, Royal Ottawa Hospital, Ontario, ON K1Z 7K4, Canada.ORCID 0000-0001-6610-9365
Raimar LoebenbergFaculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-0919-0213
Venkat BhatInterventional Psychiatry Program, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CYP450metabolismpharmacokineticspsilocybin

Identifiers

PMID40284409
PMCPMC12030428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.