Evidence map›Paper›PMID 40284379›Full record

ArticlePolymers2025

Light-Mediated 3D-Printed Wound Dressings Based on Natural Polymers with Improved Adhesion and Antioxidant Properties.

Rute Silva, Matilde Medeiros, Carlos T B Paula, Sofia Saraiva, Rafael C Rebelo, Patrícia Pereira, Jorge F J Coelho, Arménio C Serra, Ana C Fonseca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rute SilvaCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.
Matilde MedeirosCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.
Carlos T B PaulaCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.ORCID 0000-0003-2728-160X
Sofia SaraivaCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.ORCID 0000-0002-0330-1859
Rafael C RebeloCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.ORCID 0000-0003-0317-9504
Patrícia PereiraCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.ORCID 0000-0002-5665-5271
Jorge F J CoelhoCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.
Arménio C SerraCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.
Ana C FonsecaCEMMPRE, ARISE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Polo II, 3030-790 Coimbra, Portugal.

Funding

FEDER-European Regional Development Fund CENTRO-07-CT62-FEDER-002012FEDER-European Regional Development Fund UID/EMS/00285/2020Fundação para a Ciência e Tecnologia (FCT) 2021.08025.BDFundação para a Ciência e Tecnologia (FCT) LA/P/0112/2020Fundação para a Ciência e Tecnologia (FCT) REEQ/481/QUI/2006, RECI/QEQ-QFI/0168/2012
6 · The paper itself

Abstract

The lack of personalized wound dressings tailored to individual needs can significantly hinder wound healing. Hydrogels offer a promising solution, as they can be engineered to mimic the extracellular matrix (ECM), providing an optimal environment for wound repair. The integration of digital light processing (DLP), a high-resolution 3D printing process, allows precise customization of hydrogel-based wound dressings. In this study, gelatin methacrylate (GelMA)-based formulations were prepared in combination with three different polymeric precursors: methacrylated hyaluronic acid (HAMA), poly (ethylene glycol) diacrylate (PEGDA) and allyl cellulose (MCCA). These precursors were used to print high-resolution micropatterned patches. The printed constructs revealed a high gel content and a good resistance to hydrolytic degradation. To improve the adhesive and antioxidant properties of the printed patches, gallic acid (GA) was incorporated through surface functionalization. This enabled the scavenging of approximately 80% of free radicals within just 4 h. The adhesive properties of the printed wound dressings were also significantly improved, with further enhancement observed upon the addition of Fe

Indexed as

3D printingadhesion propertiesantioxidant propertiesdigital light processing (DLP)hydrogelmicropatterned structureswound healing

Identifiers

PMID40284379
PMCPMC12031436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.