Evidence map›Paper›PMID 40284213›Full record

ArticleNutrients2025

Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice.

Gessica Lioci, Fabio Gurrado, Nadia Panera, Marzia Bianchi, Cristiano De Stefanis, Valentina D'Oria, Nicolò Cicolani, Silvano Junior Santini, Laura Schiadà, Anna Alisi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. PreliminaryLife (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gessica LiociLiver Injury and Transplant Unit, Polytechnic University of Marche, 60121 Ancona, Italy.
Fabio GurradoLiver Injury and Transplant Unit, Polytechnic University of Marche, 60121 Ancona, Italy.
Nadia PaneraResearch Unit of Genetics of Complex Phenotypes, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Marzia BianchiResearch Unit of Genetics of Complex Phenotypes, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Cristiano De StefanisCore Facilities, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0001-5898-9518
Valentina D'OriaCore Facilities, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Nicolò CicolaniCore Facilities, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0003-3297-1592
Silvano Junior SantiniDepartment of Life, Health and Environmental Sciences-MESVA, School of Emergency-Urgency Medicine, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0001-6577-5892
Laura SchiadàLiver Injury and Transplant Unit, Polytechnic University of Marche, 60121 Ancona, Italy.
Anna AlisiResearch Unit of Genetics of Complex Phenotypes, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-7241-6329
Gianluca Svegliati-BaroniLiver Injury and Transplant Unit, Polytechnic University of Marche, 60121 Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fatty LiverIntestinal MucosaLiver X ReceptorsNon-alcoholic Fatty Liver DiseaseAnimalsCholesterolDiet, WesternDisease Models, AnimalLipid MetabolismLipoproteins, HDLLiverLiver CirrhosisMaleMiceMice, Inbred C57BLScavenger Receptors, Class BCholesterolLipoproteins, HDLLiver X ReceptorsNr1h3 protein, mouseScarb1 protein, mouseScavenger Receptors, Class BTriglyceridesHDLinflammationintestineliver fibrosisliver X receptorMASHMASLDSRB1

Identifiers

PMID40284213
PMCPMC12030714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.