Evidence map›Paper›PMID 40284036›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Assessing Omega-3 Therapy and Its Cardiovascular Benefits: What About Icosapent Ethyl? A Systematic Review and Meta-Analysis.

Nathália Mendes Machado, Maria Vitória Barroso Oliveira, Karina Quesada, Jesselina Francisco Dos Santos Haber, Ricardo José Tofano, Claudio José Rubira, Tereza Lais Menegucci Zutin, Rosa Direito, Eliana de Souza Bastos Mazuqueli Pereira, Camila Marcondes de Oliveira and 6 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. DHA ModulatesInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nathália Mendes MachadoDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Maria Vitória Barroso OliveiraDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Karina QuesadaDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Jesselina Francisco Dos Santos HaberDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Ricardo José TofanoDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Claudio José RubiraDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Tereza Lais Menegucci ZutinDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Rosa DireitoLaboratory of Systems Integration Pharmacology, Clinical and Regulatory Science, Research Institute for Medicines, Universidade de Lisboa (iMed.ULisboa), Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.ORCID 0000-0002-4143-4302
Eliana de Souza Bastos Mazuqueli PereiraPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Camila Marcondes de OliveiraDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.ORCID 0000-0003-4715-6160
Ricardo de Alvares GoulartDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.
Vitor Engrácia ValentiFaculty of Philosophy and Sciences, Universidade Estadual Paulista (UNESP), Marília 17525-900, São Paulo, Brazil.
Kátia Portero SloanDepartment of Clinical Metabolism, Texas Institute for Kidney and Endocrine Disorders (TIKED), Lufkin, TX 75904, USA.
Lance Alan SloanDepartment of Clinical Metabolism, Texas Institute for Kidney and Endocrine Disorders (TIKED), Lufkin, TX 75904, USA.
Lucas Fornari LaurindoDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.ORCID 0000-0003-3159-0982
Sandra Maria BarbalhoDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília 17525-902, São Paulo, Brazil.ORCID 0000-0002-5035-876X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiovascular diseaseseicosapentaenoic acidEPAIcosapent ethyllipid-lowering therapieslipids

Identifiers

PMID40284036
PMCPMC12030327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.