Evidence map›Paper›PMID 40284004›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Tauroursodeoxycholic Acid Protects Retinal Ganglion Cells and Reduces Inflammation in Mice Following Optic Nerve Crush.

Nan Zhang, Ying Li, Xian Zhang, Micah A Chrenek, Jiaxing Wang, Preston E Girardot, Jana T Sellers, Eldon E Geisert, John M Nickerson, Jeffrey H Boatright

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nan ZhangAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.ORCID 0000-0003-3249-1863
Ying LiAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.ORCID 0000-0002-9615-4914
Xian ZhangAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.
Micah A ChrenekDepartment of Ophthalmology, School of Medicine, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-1366-5963
Jiaxing WangDepartment of Ophthalmology, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Preston E GirardotAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.
Jana T SellersAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.
Eldon E GeisertDepartment of Ophthalmology, School of Medicine, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0003-0787-4416
John M NickersonDepartment of Ophthalmology, School of Medicine, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0003-2419-9897
Jeffrey H BoatrightAtlanta Veterans Administration Center for Visual and Cognitive Rehabilitation, Decatur, GA 30033, USA.ORCID 0000-0001-5875-492X

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
VIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6M
NEI NIH HHS P30 EY006360NEI NIH HHS T32 EY007092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bile acidinflammationmicemousemus musculusoptic nerve crushretinal ganglion celltauroursodeoxycholic acid

Identifiers

PMID40284004
PMCPMC12030659

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.