Evidence map›Paper›PMID 40283508›Full record

ReviewJournal of clinical medicine2025

Key Insights into Gut Alterations in Metabolic Syndrome.

Adrian Boicean, Cristian Ichim, Sabina-Maria Sasu, Samuel Bogdan Todor

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
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  8. The Impact of Obesity onJournal of clinical medicine · 2025
    Article
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  12. Article
  13. Article
  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adrian BoiceanFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0002-6646-1585
Cristian IchimFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.ORCID 0009-0005-9111-6088
Sabina-Maria SasuFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Samuel Bogdan TodorFaculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over time, extensive research has underscored the pivotal role of gut microbiota in the onset and progression of various diseases, with a particular focus on fecal microbiota transplantation (FMT) as a potential therapeutic approach. The practice of transferring fecal matter from a healthy donor to a patient provides valuable insights into how alterations in gut microbiota can impact disease development and how rectifying dysbiosis may offer therapeutic benefits. Re-establishing a balanced symbiotic relationship in the gastrointestinal tract has shown positive results in managing both intestinal and systemic conditions. Currently, one of the most pressing global health issues is metabolic syndrome-a cluster of conditions that includes insulin resistance, lipid imbalances, central obesity and hypertension. In this context, FMT has emerged as a promising strategy for addressing key components of metabolic syndrome, such as improving insulin sensitivity, body weight and lipid profiles. However, further well-structured studies are needed to refine treatment protocols and establish the long-term safety and efficacy of this intervention.

Indexed as

dyslipidemiaFMTguthypertensionobesity

Identifiers

PMID40283508
PMCPMC12028006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.