ReviewJournal of clinical medicine2025
Rethinking the Assessment of Arthrogenic Muscle Inhibition After ACL Reconstruction: Implications for Return-to-Sport Decision-Making-A Narrative Review.
Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Effects of contralateral knee functional training on knee function, pain, kinesiophobia, plantar load distribution, and stance-phase parameters after anterior cruciate ligament reconstruction: a single-blind, randomised controlled trial.BMC musculoskeletal disorders · 2026Trial
- Blood flow restriction as an adjunct during mid-stage rehabilitation after ACL reconstruction: a randomized sham-controlled study.BMC musculoskeletal disorders · 2026Trial
- Eccentric Hamstring Force Asymmetry After Anterior Cruciate Ligament Reconstruction: A Cross-Sectional Comparison of Independent 12- and 24-Month Postoperative Cohorts.Diagnostics (Basel, Switzerland) · 2026Article
- FIRM-P separates knee phenotype from patient context in anterior cruciate ligament-related instability: A conceptual framework integrating arthrogenic muscle inhibition as a cross-domain modifier.Journal of experimental orthopaedics · 2026Article
- The Role of Nootropic Supplements in Sports: Enhancing Cognitive and Physical Performance Simultaneously.Food science & nutrition · 2026Review
- Relationship Between Knee Muscle Strength Symmetry and Lower Limb Landing Mechanics Following ACL Reconstruction.Sports medicine - open · 2026Article
- Periodization in Orthobiologics Rehabilitation.Journal of clinical medicine · 2026Article
- Comparison of gait characteristics at different postoperative phases following anterior cruciate ligament reconstruction.BMC sports science, medicine & rehabilitation · 2026Article
- Effectiveness of Transcutaneous and Percutaneous Electrical Nerve Stimulation as Adjunct Therapies in Patients After Anterior Cruciate Ligament Reconstruction: Study Protocol for a Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Triceps Surae Neuromuscular Activity During Single-leg Jumping Tasks in Individuals After Anterior Cruciate Ligament Reconstruction.International journal of sports physical therapy · 2026Article
- Functional proprioceptive stimulation promotes early rehabilitation following ACL reconstruction: a randomized controlled trial.Frontiers in rehabilitation sciences · 2026Article
- Dual-Task Single-Leg Hop Performance Exposes Persistent Asymmetry and Movement Deficits After Anterior Cruciate Ligament Reconstruction: A Randomised Crossover Experimental Study.Translational sports medicine · 2026Article
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- Evidence Summary for Early-Stage Rehabilitation After Anterior Cruciate Ligament Reconstruction.Journal of multidisciplinary healthcare · 2026Review
- Postural control characteristics as reflected by center of pressure measurements in anterior cruciate ligament reconstruction patients at varying post-operative stages: a cross-sectional comparative study.Journal of orthopaedic surgery and research · 2026Article
- Learning, Communication, and Use of Evidence Based Practice in Anterior Cruciate Ligament Reconstruction Rehabilitation: An Exploratory Survey of French Physiotherapists.International journal of sports physical therapy · 2026Article
- Intra-Session Reliability of Eccentric Countermovement Jump Kinetics in Individuals Six Months After Anterior Cruciate Ligament Reconstruction.International journal of sports physical therapy · 2026Article
- Conditioned pain modulation, cortical imbalance, and arthrogenic muscle inhibition: an integrative model with implications for exercise in chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Anterior Cruciate Ligament Reconstruction Rehabilitation as a Complex Adaptive Process: From Control-Chaos to Actionable Return-to-Sport Decisions.Bioengineering (Basel, Switzerland) · 2025Article
- Evidence for arthrogenic inhibition of the gluteus medius after anterior cruciate ligament injury: A systematic review.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arthrogenic muscle inhibition (AMI) is a neuromuscular impairment commonly observed following anterior cruciate ligament reconstruction (ACLR). This condition, characterized by persistent quadricep inhibition due to altered afferent feedback, significantly impacts neuromuscular recovery, delaying return to running and sport. Despite advancements in rehabilitation strategies, AMI may persist for months or even years after ACLR, leading to muscle strength asymmetries, altered biomechanics, and an increased risk of reinjury. The mechanisms underlying AMI involve both peripheral (joint effusion, mechanoreceptor dysfunction) and central (corticospinal inhibition, neuroplasticity alterations) components, which collectively hinder voluntary muscle activation and movement control. AMI alters gait mechanics, reduces knee stability, and promotes compensatory patterns that increase injury risk. Current return-to-sport protocols emphasize strength symmetry and functional performance but often neglect neuromuscular deficits. A comprehensive assessment integrating neuromuscular, biomechanical, and proprioceptive evaluations is needed at specific stages to optimize rehabilitation and minimize reinjury risk. Future research should explore targeted interventions such as neuromuscular stimulation, cognitive-motor training, and advanced gait analysis to mitigate AMI's impact and facilitate a safer, more effective return to sport.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.