ArticleLife (Basel, Switzerland)2025
Non-Invasive Spectroscopic Determination of the Skin and Blood Carotenoids of Term and Preterm Infants in the First Month of Life and the Influence of Free Radical-Mediated Diseases.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postpartum adaptation causes an increased formation of free radicals (FRs) in the organism, which can lead to development of various FR-mediated diseases (FRMDs) in the newborn. The present study investigates the kinetics of skin and blood carotenoid antioxidants in term and preterm infants and the influence of FRMD. In the first phase, a diffuse reflectance spectroscopy-based scanner was validated for non-invasive measurements of skin carotenoids in term infants (thenar eminence) by correlation with blood carotenoids via reflection spectroscopy. In the second phase, the skin and blood carotenoids of 22 term and 13 preterm infants with and without FRMD were assessed from birth until discharge. It could be shown that the scanner reliably assessed carotenoids in the infants' skin. The term and preterm infants showed similar kinetics of skin carotenoids, which increased and entered a plateau after 3-4 days. In our cohort, FRMD did not have a significant influence on skin carotenoid concentration. This was due to immature sweat glands and an insufficient excretion of carotenoids. Skin carotenoids seem to be unavailable, suggesting that they may have to be supplemented in infants with FRMD. Blood carotenoid concentrations tended to be lower in preterm infants and infants with FRMD compared to healthy term infants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.