Evidence map›Paper›PMID 40283064›Full record

ArticleLife (Basel, Switzerland)2025

Navigating the Labial Artery: A Safer Approach to Submucosal Lip Filler Techniques.

Bruna S F Bravo, Leonardo G Bravo, Beatriz G Cornachini, Mariana C Elias, Gabriel L T Alves

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bruna S F BravoDepartment of Dermatology, Bravo Private Clinic, Avenida Ataulfo de Paiva 245 Quinto Andar Leblon, Rio de Janeiro 20440-032, Brazil.
Leonardo G BravoDepartment of Dermatology, Bravo Private Clinic, Avenida Ataulfo de Paiva 245 Quinto Andar Leblon, Rio de Janeiro 20440-032, Brazil.
Beatriz G CornachiniDepartment of Dermatology, Bravo Private Clinic, Avenida Ataulfo de Paiva 245 Quinto Andar Leblon, Rio de Janeiro 20440-032, Brazil.
Mariana C EliasDepartment of Dermatology, Bravo Private Clinic, Avenida Ataulfo de Paiva 245 Quinto Andar Leblon, Rio de Janeiro 20440-032, Brazil.
Gabriel L T AlvesDepartment of Dermatology, Bravo Private Clinic, Avenida Ataulfo de Paiva 245 Quinto Andar Leblon, Rio de Janeiro 20440-032, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lip augmentation using hyaluronic acid (HA) fillers has become one of the most popular non-surgical aesthetic procedures, yet it is not without risks, particularly vascular complications. This study explores a novel vertical injection technique for submucosal placement of HA fillers, designed to enhance safety and achieve natural-looking outcomes. Ten patients underwent lip augmentation using the proposed technique, which involved ultrasound-guided injections at predefined entry points to target intralabial compartments while minimizing the risk of labial artery injury. The results demonstrated high patient satisfaction, with significant improvements in lip volume and contour. The submucosal placement yielded subtle, natural results with fewer visible irregularities compared to superficial injections. No major complications, such as vascular occlusion, were observed, and minor side effects, including transient swelling and redness, resolved within 48 h. The use of ultrasound imaging allowed precise filler placement and reduced the risks associated with traditional horizontal injection paths parallel to the labial arteries. While the findings highlight the technique's potential in terms of safety and efficacy, limitations include the small sample size, short-term follow-up, and the absence of a control group. Further studies with larger cohorts and comparative analyses are needed to validate long-term outcomes. This innovative approach underscores the importance of anatomical precision and advanced imaging technologies in enhancing safety and aesthetic outcomes in lip augmentation.

Indexed as

hyaluronic acidlabial arterylip augmentationsubmucosal layerultrasound

Identifiers

PMID40283064
PMCPMC12028560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.