Evidence map›Paper›PMID 40282985›Full record

Observational studyMedicina (Kaunas, Lithuania)2025

Regional and Gender-Based Distribution of KRAS Mutations in Metastatic Colorectal Cancer Patients in Turkey: An Observational Study.

Nurullah Ilhan, Faysal Dane, Erdem Goker, Kazım Uygun, Bülent Orhan, Kerem Okutur, İlkay Tuğba Ünek, Abdurrahman Işıkdoğan, Ahmet Bilici, Nurullah Zengin and 7 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nurullah IlhanDepartment of Medical Oncology, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, University of Health Sciences, 34785 Istanbul, Turkey.ORCID 0000-0001-9908-9284
Faysal DaneDepartment of Medical Oncology, Faculty of Medicine, Marmara University, 34865 Istanbul, Turkey.
Erdem GokerDepartment of Medical Oncology, Faculty of Medicine, Ege University, 35040 İzmir, Turkey.ORCID 0000-0001-6180-713X
Kazım UygunDepartment of Medical Oncology, Faculty of Medicine, Kocaeli University, 41285 Kocaeli, Turkey.
Bülent OrhanDepartment of Medical Oncology, Acıbadem Bursa Hospital, 16210 Bursa, Turkey.
Kerem OkuturDepartment of Medical Oncology, Samsun Training and Research Hospital, University of Health Sciences, 55090 Samsun, Turkey.ORCID 0000-0002-8079-7739
İlkay Tuğba ÜnekDepartment of Medical Oncology, İzmir Tepecik Training and Research Hospital, University of Health Sciences, 06080 İzmir, Turkey.ORCID 0000-0002-9124-6123
Abdurrahman IşıkdoğanDepartment of Medical Oncology, Faculty of Medicine, Dicle University, 21280 Diyarbakır, Turkey.
Ahmet BiliciDepartment of Medical Oncology, Şişli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, 34096 Istanbul, Turkey.
Nurullah ZenginDepartment of Medical Oncology, Ankara Numune Training and Research Hospital, University of Health Sciences, 06100 Ankara, Turkey.
Necati AlkışDepartment of Medical Oncology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, University of Health Sciences, 06200 Ankara, Turkey.
İdris YücelDepartment of Medical Oncology, Faculty of Medicine, Ondokuz Mayıs University, 55270 Samsun, Turkey.
Hatice OdabaşDepartment of Medical Oncology, Haydarpasa Numune Training Research Hospital, University of Health Sciences, Istanbul 34785, Turkey.ORCID 0000-0002-5757-4705
Berna Ömür ÖksüzoğluDepartment of Medical Oncology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, University of Health Sciences, 06200 Ankara, Turkey.
Akif DoğanDepartment of Medical Oncology, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, University of Health Sciences, 34785 Istanbul, Turkey.ORCID 0000-0003-4275-2414
Hande Nur ErölmezDepartment of Medical Oncology, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, University of Health Sciences, 34785 Istanbul, Turkey.ORCID 0009-0004-3791-9157
Mahmut GümüşDepartment of Medical Oncology, Istanbul Dr. Lütfi Kırdar Kartal Training and Research Hospital, Istanbul 34890, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal NeoplasmsMutationProto-Oncogene Proteins p21(ras)AdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedSex FactorsTurkeyKRAS protein, humanProto-Oncogene Proteins p21(ras)anti-EGFR resistancecodon 12 mutationcodon 13 mutationG12DG13Dgender differencesKRAS mutationmetastatic colorectal cancerpredictive biomarkersregional variation

Identifiers

PMID40282985
PMCPMC12028875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.