ArticleCancers2025
Inflammation and Thyroid Cancer: Deciphering the Role of Blood Immune Indexes.
Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy and association with lymph node metastasis of the systemic immune-inflammation index in thyroid cancer: a systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- The Role of Preoperative Radiological, Cytological, and Systemic Inflammatory Markers in Predicting Incidental Papillary Microcarcinoma in Patients with Multinodular Goiter: A Retrospective Single-Center Study.Journal of clinical medicine · 2026Article
- Association Between Systemic Immune-Inflammation Index and Thyroid Function: A Cross-Sectional Population-Based Study.International journal of endocrinology · 2026Article
- Association of Anti-TPO Antibody and Inflammatory Markers with Thyroid Ultrasound FindingsEndocrine, metabolic & immune disorders drug targets · 2026Article
- The role of cellular heterogeneity in thyroid cancer: a multi-modal analysis approach with Mendelian randomization.Discover oncology · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation within tumor microenvironments has been correlated to numerous malignancies. This study aims to explore its significance in thyroid cancer (TC).
methodsRetrospective analysis of 157 thyroid carcinomas and 40 benign cases involved initial univariate analysis. The value of neutrophils/value of lymphocytes (NLR), value of platelets/value of lymphocytes (PLR), value of lymphocytes/value of monocytes (LMR), and value of platelets × value of neutrophils/value of lymphocytes (SII) indexes were related to TC characteristics and number and location of involved lymph nodes using χ
resultsThe SII index emerged as a predictor of malignancy in both univariate and multivariate analyses (
conclusionsThe SII index appears to be a valuable tool in the presence of TC, showing correlations with malignancy, tumor size, and CLNMs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.