Evidence map›Paper›PMID 40282526›Full record

ReviewCancers2025

Impact of PSMA-PET/CT on Radiotherapy Decisions: Is There a Clinical Benefit?

Elías Gomis-Sellés, Antonio Maldonado, Miren Gaztañaga, Victoria Vera, Odile Ajulia, Gemma Sancho, Shankar Siva, Fernando Lopez-Campos, Felipe Couñago

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elías Gomis-SellésDepartment of Radiation Oncology, Hospital Clínic Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-9924-7561
Antonio MaldonadoNuclear Medicine and Molecular Imaging Department, University Hospital Quironsalud Madrid/La Luz Hospital, 28003 Madrid, Spain.ORCID 0000-0002-7488-5978
Miren GaztañagaDepartment of Radiation Oncology, San Carlos Hospital, Genesis Care Vithas La Milagrosa, 28010 Madrid, Spain.ORCID 0009-0007-5803-1108
Victoria VeraDepartment of Radiation Oncology, Badajoz University Hospital, 06006 Badajoz, Spain.ORCID 0000-0003-4841-0394
Odile AjuliaNuclear Medicine Department, University Hospital Ramon y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-2020-5391
Gemma SanchoDepartment of Radiation Oncology, Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, Spain.
Shankar SivaPeter MacCallum Cancer Centre, Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville 3010, Australia.ORCID 0000-0003-2840-0658
Fernando Lopez-CamposDepartment of Radiation Oncology, Hospital Universitario Ramón y Cajal, Genesis Care Vithas La Milagrosa, 28010 Madrid, Spain.ORCID 0000-0002-4077-0507
Felipe CouñagoGenesiscare España, Hospital Universitario San Francisco de Asis, Hospital Universitario La Milagrosa, Universidad Europea de Madrid, 28670 Madrid, Spain.ORCID 0000-0001-7233-0234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) has emerged as a game-changing imaging modality in prostate cancer, offering superior sensitivity and specificity compared to conventional imaging techniques. Its increasing adoption has significantly influenced radiotherapy decision-making, yet its true clinical impact remains under investigation. This narrative review explores the role of PSMA-PET/CT in guiding radiotherapy decisions across different clinical scenarios, from primary treatment planning to biochemical recurrence and oligometastatic disease. We assess its impact on target delineation, treatment modifications, and overall patient management while addressing existing knowledge gaps.

Indexed as

androgen deprivation therapybiochemical recurrencemetastasis-directed therapyPET-based treatment planningprostate cancerPSMAradiotherapysalvage radiotherapytarget volume delineation

Identifiers

PMID40282526
PMCPMC12025452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.