Evidence map›Paper›PMID 40282513›Full record

ReviewCancers2025

Surveillance After Focal Therapy for Prostate Cancer: A Comprehensive Review.

Jason Koehler, Simon Han, Samuel Tremblay, Wei-Wen Hsu, Bora Kalaycioglu, Aytekin Oto, Abhinav Sidana

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. MR Imaging/Ultrasound Fusion-Guided Biopsy and Primary Focal Therapy for Localized Prostate Cancer.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jason KoehlerCollege of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.ORCID 0000-0003-4533-3813
Simon HanPritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-5743-2010
Samuel TremblaySection of Urology, Department of Surgery, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-0982-655X
Wei-Wen HsuDivision of Biostatistics and Bioinformatics, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.ORCID 0000-0002-7822-0826
Bora KalayciogluDepartment of Radiology, University of Chicago, Chicago, IL 60637, USA.
Aytekin OtoDepartment of Radiology, University of Chicago, Chicago, IL 60637, USA.
Abhinav SidanaSection of Urology, Department of Surgery, University of Chicago, Chicago, IL 60637, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focal Therapy (FT) is an emerging treatment modality for prostate cancer (PCa). Due to its novelty, the research exploring how patients should be followed-up after treatment is limited. There is currently no established role for non-prostate-specific-antigen (PSA) biomarkers and PSMA PET. However, a combination of PSA testing, multiparametric magnetic resonance imaging (mpMRI), and systematic and targeted biopsies should routinely be used for surveillance after FT. PSA values that rise 1.0 ng/mL over the nadir after twelve months or rise 1.5 ng/mL over nadir after twenty-four to thirty-six months should raise suspicion for recurrence. The standard imaging technique is mpMRI, but it can often be difficult to interpret after FT, so using a scoring system such as prostate imaging after focal ablation (PI-FAB) or the transatlantic recommendations for prostate gland evaluation with magnetic resonance imaging after focal therapy (TARGET) allows for greater consistency between readers. This review seeks to summarize the current literature regarding surveillance after FT as it relates to biomarkers, imaging, biopsies, and consensus statements.

Indexed as

failurefocal therapyprostate cancersurveillance

Identifiers

PMID40282513
PMCPMC12025428

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.