Evidence map›Paper›PMID 40282486›Full record

ReviewCancers2025

Addressing Akrasia in Childhood, Adolescent and Young Adult Cancer Survivors: Implications for Long-Term Follow-Up and Preventive Health Interventions.

Charlotte Demoor-Goldschmidt, Kristopher Lamore, Zsuzsanna Jakab, Maëlle de Ville de Goyet, Sabine Heinrich, Laura Bathilde, Claire Berger, Laura Beek, Marion Beauchesne, Erika Borszekine Cserhati and 17 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Charlotte Demoor-GoldschmidtPediatric Oncology-Hematology-Immunology Department, University Hospital of Angers, 49933 Angers, France.ORCID 0000-0002-1236-9089
Kristopher LamoreUniv. Lille, CNRS, UMR 9193-SCALab-Sciences Cognitives et Sciences Affectives, F 59000 Lille, France.ORCID 0000-0002-8878-2662
Zsuzsanna JakabNational Childhood Oncologic Registry, Hungarian Pediatric Oncology Network, 1085 Budapest, Hungary.
Maëlle de Ville de GoyetPediatric Hematology and Oncology Department, Institut Roi Albert II, Cliniques Universitaires Saint-Luc and Institut de Recherche Expérimentale et Clinique, UCLouvain, 1200 Brussels, Belgium.
Sabine HeinrichLes Aguerris Association, 75014 Paris, France.
Laura BathildeLes Aguerris Association, 75014 Paris, France.
Claire BergerDepartment of Pediatric Hematology and Oncology, University-Hospital, 42055 Saint-Etienne, France.ORCID 0000-0001-9875-5150
Laura BeekDepartment of Psycho-Oncology, Princess Máxima Centre for Paediatric Oncology, 3584 CS Utrecht, The Netherlands.
Marion BeauchesneGCS HUGO, University Hospitals of "Grand Ouest", 49000 Angers, France.
Erika Borszekine CserhatiÉrintettek Association, 1088 Budapest, Hungary.
Bénédicte BrichardPediatric Hematology and Oncology Department, Institut Roi Albert II-Ethics Committee-Cliniques Universitaires Saint-Luc, UCLouvain, 1200 Brussels, Belgium.
Louis S ConstineDepartments of Radiation Oncology and Pediatrics, University of Rochester Wilmot Cancer Institute, Rochester, NY 14642, USA.
Jeroen Te DorsthorstPanCare, 1401 AZ Bussum, The Netherlands.
Michele FavreauUniversity Angers, GRANEM, SFR CONFLUENCES, 49000 Angers, France.
Desiree GrabowDivision of Childhood Cancer Epidemiology/German Childhood Cancer Registry, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Louise HinckelPediatric Oncology-Hematology-Immunology Department, University Hospital of Angers, 49933 Angers, France.ORCID 0009-0000-3812-1631
Anita KeresztesPediatric Hematology and Oncology Department, Institut Roi Albert II-Ethics Committee-Cliniques Universitaires Saint-Luc, UCLouvain, 1200 Brussels, Belgium.
Luc OllivierDepartment of Radiation Oncology, ICO, 44800 Saint Herblain, France.ORCID 0000-0002-4270-5370
Baptiste SautereyDepartment of Oncology, ICO, 49000 Angers, France.ORCID 0000-0001-9160-7307
Roderick SkinnerDepartment of Paediatric and Adolescent Haematology/Oncology, Great North Children's Hospital and Translational and Clinical Research Institute and Centre for Cancer, Newcastle NE7 7DN, UK.
Eric ThebaultDepartment of Pediatric Oncology, Oscar Lambret Center, 59000 Lille, France.ORCID 0000-0003-1327-3852
Isabelle Thierry-ChefBarcelona Institute for Global Health, 08036 Barcelona, Spain.ORCID 0000-0001-6304-2783
Sarolta TrinhHungarian Pediatric Oncology Network, 1088 Budapest, Hungary.ORCID 0000-0002-9538-0864
Lorna Zadravec ZaletelRadiotherapy Department, Institute of Oncology Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-4423-0276
Jelena RoganovicDepartment of Pediatric Hematology and Oncology, Children's Hospital Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-7960-6069
Marie-Celine Chades-EsnaultCAPHI (Centre Atlantique de Philosophie, Atlantic Centre for Philosophy), UR 7463, 44312 Nantes, France.
Aurore ArmandEREPL (Espace de Réflexion Ethique des Pays de la Loire, Ethics Reflection Space of the Pays de la Loire Region), 49000 Angers, France.

Funding

horizon europe 101136549
6 · The paper itself

Abstract

backgroundChildhood, adolescent, and young adult cancer survivors (CAYACS) face significant long-term health risks, yet adherence to long-term follow-up (LTFU) care remains inconsistent. This study explores the concept of akrasia (i.e., acting against one's better judgment by engaging in behaviors known to be harmful or counterproductive) to understand the psychological, cognitive, and systemic barriers influencing survivor engagement in LTFU.

methodUsing an ethical reflection approach based on a literature review, we discussed survivor experiences, behavioral science insights, and ethical principles to identify solutions that balance patient autonomy with supportive interventions. A narrative approach was used to summarize the key points discussed during the ethics reflection group meetings.

resultsOur findings highlight key barriers such as trauma, avoidance behaviors, and cognitive constraints that contribute to non-adherence. Strategies such as shared decision-making, digital health tools, and nudge-based interventions are proposed to enhance survivor engagement. Ethical considerations emphasize the need for personalized and flexible care approaches that respect survivor agency while mitigating obstacles to adherence.

conclusionsAddressing akrasia through ethical and behavioral frameworks could improve LTFU adherence, ultimately enhancing survivorship care and long-term health outcomes.

Indexed as

adhesionakrasiaautonomychildhood cancer survivorsnudgepatient activationscreeningshared decision-makingsurvivorshiptailored informationyoung adult cancer survivors

Identifiers

PMID40282486
PMCPMC12025612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.