ArticleCancers2025
Role of Postoperative Radiotherapy in the Management of Localized Head and Neck Mucosal Melanoma.
Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesTo evaluate the role of postoperative radiotherapy (PORT) in the management of localized head and neck mucosal melanoma (HNMM).
methodsWe retrospectively reviewed 33 patients who underwent surgery for localized HNMM between 2006 and 2023. PORT was delivered to affected anatomical structures, and elective nodal irradiation was not performed. Treatment outcomes, including local recurrence-free survival (LRFS), progression-free survival (PFS), and overall survival (OS), were analyzed.
resultsAfter surgery, 14 patients (41.4%) received PORT. During follow-up, 87.9% of patients experienced recurrence, with local and distant failures being the most common. PORT significantly improved LRFS (
conclusionsPORT for localized HNMM improved local control. Regional recurrence was rare (one patient, 3.4%) even though ENI was not performed. PORT without ENI could improve clinical outcomes for localized HNMM.
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