Evidence map›Paper›PMID 40282455›Full record

ArticleCancers2025

Cancer Cell-Intrinsic Type I Interferon Signaling Promotes Antitumor Immunity in Head and Neck Squamous Cell Carcinoma.

Guiqin Xie, Cuicui Yang, Xiaowu Pang, Tzyy-Choou Wu, Xinbin Gu

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guiqin XieDepartment of Oral Pathology, Howard University, 600 W Street NW, Washington, DC 20059, USA.ORCID 0000-0002-7616-1893
Cuicui YangDepartment of Oral Pathology, Howard University, 600 W Street NW, Washington, DC 20059, USA.
Xiaowu PangDepartment of Oral Pathology, Howard University, 600 W Street NW, Washington, DC 20059, USA.
Tzyy-Choou WuPathology, Oncology, Obstetrics & Gynecology, and Molecular Microbiology & Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Xinbin GuDepartment of Oral Pathology, Howard University, 600 W Street NW, Washington, DC 20059, USA.ORCID 0000-0003-4043-3647

Funding

Treatment of HIV- and HIV+ Patients with HPV16+ CIN2/3 Using pNGLV4a-hCRTE6E7L2 DNA vaccine administered intramuscularly via electroporationP50CA098252 · NCI · JOHNS HOPKINS UNIVERSITY · PI WARNER KING HUH, TZYY-CHOOU WU · 2003 to 2026
$53.5M
NCI NIH HHS P50 CA098252the American Cancer Society Diversity in Cancer Research Institutional Development Grant at Howard University pilot award DICRIDG-21-074-01the Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) Pilot Translational and Clinical Studiesthe National Institute of Health R25DE032527
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dendritic cellhead and neck cancerHNSCCinnate immunitytype I interferon

Identifiers

PMID40282455
PMCPMC12025670

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.