Evidence map›Paper›PMID 40282446›Full record

ArticleCancers2025

The Influence of the Germline

Samuel Kellen, Allison Makovec, Carly D Miller, Shayan S Nazari, Andrew Elliott, Aiden Deacon, Emily John, Nikitha Vobugari, Neeraj Agarwal, Rana R McKay and 5 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Samuel KellenMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0009-0004-7888-4376
Allison MakovecMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0009-0008-2487-9079
Carly D MillerMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0009-0008-7609-0782
Shayan S NazariCaris Life Sciences, Phoenix, AZ 85040, USA.
Andrew ElliottCaris Life Sciences, Phoenix, AZ 85040, USA.ORCID 0000-0001-8494-8031
Aiden DeaconMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Emily JohnMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0009-0008-1408-1573
Nikitha VobugariDepartment of Medicine, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA.
Neeraj AgarwalDivision of Hematology and Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake, UT 84112, USA.ORCID 0000-0003-1076-0428
Rana R McKayDepartment of Radiation Medicine and Applied Sciences, UC San Diego School of Medicine, La Jolla, CA 92093, USA.
Pedro C BarataUniversity Hospitals Seidman Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0002-8890-2951
Charles J RyanMemorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Nima SharifiDesai Sethi Urology Institute and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-1281-3474
Justin HwangMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1686-7103
Emmanuel S AntonarakisMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-3531-3851

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
Interactions of Androgen Production, Uptake and Metabolism on outcome in Castration Resistant Prostate CancerR01CA249279 · NCI · UNIVERSITY OF MINNESOTA · PI HALABI, SUSAN, SHARIFI, NIMA · 2021 to 2024
$2.1M
Dissecting mechanisms of sensitivity to B7-H3 (CD276)-targeted therapeutics in prostate cancer (PC)R37CA288972 · NCI · UNIVERSITY OF MINNESOTA · PI Justin H. Hwang · 2024 to 2026
$1.1M
Department of Defense W81XWH-22-2-0025NCI NIH HHS P30 CA008748NIH HHS 5R01CA172382NIH HHS 5R01CA249279NIH HHS P30 CA077598NIH HHS R01 CA249279NIH HHS R37 CA288972
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

geneticsgenomicsHSD3B1immunologyprostate cancertranscriptomics

Identifiers

PMID40282446
PMCPMC12025685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.