Evidence map›Paper›PMID 40282408›Full record

ArticleGenes2025

G0S2 Promotes PD-L1 Expression in Monocytes and Influences the Efficacy of PD-1 Inhibitors in Hepatocellular Carcinoma.

Xuanshuang Du, Wenwen Zhang, Sujuan Sun, Chenghao Liu, Yuanying He, Fengling Luo, Hongyan Wu, Min Liu

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Recent advances on the role of G0S2.Discover oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuanshuang DuDepartment of Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Wenwen ZhangDepartment of Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Sujuan SunDepartment of Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Chenghao LiuDepartment of Pathology, TaiKang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Yuanying HeDepartment of Pathology, TaiKang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Fengling LuoDepartment of Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.
Hongyan WuHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang 443002, China.ORCID 0000-0002-4144-3065
Min LiuDepartment of Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan 430071, China.ORCID 0000-0001-7095-1344

Funding

National Natural Science Foundation of China grants 82272978
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B7-H1 AntigenCarcinoma, HepatocellularImmune Checkpoint InhibitorsLiver NeoplasmsMonocytesCD8-Positive T-LymphocytesCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedProgrammed Cell Death 1 ReceptorTumor MicroenvironmentB7-H1 AntigenCD274 protein, humanImmune Checkpoint InhibitorsProgrammed Cell Death 1 ReceptorG0S2hepatocellular carcinomaPD-1 inhibitorsPD-L1T cell response

Identifiers

PMID40282408
PMCPMC12027009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.