Evidence map›Paper›PMID 40282310›Full record

ArticleBiology2025

CRISPR/Cas9-Mediated Development of Potato Varieties with Long-Term Cold Storage and Bruising Resistance.

Gabriela Alejandra Massa, Cecilia Andrea Décima Oneto, Matías Nicolás González, Anabela Poulsen Hornum, Ailín Arizmendi, Sofía Sucar, Silvina Beatriz Divito, Sergio Enrique Feingold

Erratum issuedAbstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025
    Review
  7. Review
  8. Article
  9. CRISPR/Cas9 editing ofFrontiers in plant science · 2025
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Gabriela Alejandra MassaLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0000-0002-9028-1330
Cecilia Andrea Décima OnetoLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0000-0003-1136-462X
Matías Nicolás GonzálezLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0000-0003-3700-4382
Anabela Poulsen HornumLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0009-0002-1613-8031
Ailín ArizmendiLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0009-0004-2738-3336
Sofía SucarLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.
Silvina Beatriz DivitoLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.
Sergio Enrique FeingoldLaboratorio de Agrobiotecnología, EEA Balcarce-IPADS (UEDD INTA-CONICET), Instituto Nacional de Tecnología Agropecuaria (INTA), Balcarce B7620, Argentina.ORCID 0000-0002-7107-4651

Funding

Biodesarrollar 81FONTAGRO ATN/RF-18757-RGINTA PD-I086INTA PD-I127INTA PE-I115INTA FVT 63PICT 2011-411PICT Start-up 2018-0899
6 · The paper itself

Abstract

Enzymatic browning and cold-induced sweetening (CIS) affect the post-harvest quality of potato tubers. Browning is caused by polyphenol oxidase 2 (PPO2), which is activated by mechanical damage during harvest and storage. CIS occurs when vacuolar invertase converts sucrose into reducing sugars, which react with amino acids during frying, forming brown pigments and acrylamide. While cold storage prevents sprouting and disease, it also increases vacuolar invertase expression, leading to quality loss. Using CRISPR/Cas9, we developed gene-edited potato lines with improved resistance to browning and CIS. Line 6A (cv. Atlantic) and E03-3 (cv. Spunta) exhibited complete vacuolar invertase (

Indexed as

cold-induced sweeteningenzymatic browninggenome editingmulti-targetpolyphenol oxidaseribonucleoproteinSolanum tuberosumvacuolar invertase

Identifiers

PMID40282310
PMCPMC12024581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.