Evidence map›Paper›PMID 40282199›Full record

ArticleBiology2025

Effects of Acidic Polysaccharide-Enriched Extracts from

Cristina Ciampelli, Sylvia Mangani, Gabriele Nieddu, Marilena Formato, Paraskevi Ioannou, Spyros Kremmydas, Nikos Karamanos, Antonio Junior Lepedda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects of Protease-Hydrolyzed andFoods (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristina CiampelliDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-1761-3124
Sylvia ManganiBiochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0009-0002-2013-7189
Gabriele NiedduDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-9268-9436
Marilena FormatoDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0001-9207-5787
Paraskevi IoannouBiochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0009-0000-8207-8263
Spyros KremmydasBiochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0009-0006-5079-3274
Nikos KaramanosBiochemistry, Biochemical Analysis & Matrix Pathobiology Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-3618-0288
Antonio Junior LepeddaDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-8356-894X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine invertebrates, particularly Holothurians, have emerged as valuable sources of bioactive compounds with potential anticancer properties. In this study, we investigated the effects of two acidic polysaccharide-enriched (APs) fractions (Ht1 and Ht2) from the sea cucumber species

Indexed as

acidic polysaccharides (APs)anticancer propertiesbreast cancerepithelial–mesenchymal transition (EMT)marine invertebrates

Identifiers

PMID40282199
PMCPMC12025287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.