Evidence map›Paper›PMID 40281981›Full record

ArticleAnimals : an open access journal from MDPI2025

Impact of Flavonoid-Enriched Antioxidant Nanoformulation Supplementation on In Vitro Maturation and Gene Expression of Buffalo Oocytes.

Eman M El-Saka, Abou Bakr A El-Wishy, Adel R Moawad, Sally Ibrahim, Saber Ibrahim, Abdallah M Shahat

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eman M El-SakaDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Abou Bakr A El-WishyDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Adel R MoawadDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0003-4397-9688
Sally IbrahimDepartment of Animal Reproduction and AI, Veterinary Research Institute, National Research Centre, Giza 12622, Egypt.
Saber IbrahimPackaging Materials Department, National Research Centre, Dokki, Giza 12622, Egypt.ORCID 0000-0003-2509-3832
Abdallah M ShahatDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0001-5519-0743

Funding

Adel R. Moawad is supported by research grants from National Institute of Food and Agriculture, U.S. Department of Agriculture, 1890 Capacity Building Grant (grant# 2022-09585) and Evans-Allen Grant (grant# 1025736)
6 · The paper itself

Abstract

Oocytes are exposed to various stressors during in vitro maturation (IVM). Antioxidant supplementation during IVM can mitigate oxidative stress. We investigated the effects of supplementing IVM medium with novel flavonoid-enriched antioxidant nanoformulations, namely, EMD-300

Indexed as

antioxidantsbuffaloflavonoidsgene expressionIVMnanoparticlesoocyte

Identifiers

PMID40281981
PMCPMC12024126

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.