Evidence map›Paper›PMID 40281937›Full record

ArticleAnimals : an open access journal from MDPI2025

Associations Between Non-Steroidal and Steroidal Anti-Inflammatory Drug Use, Welfare, and Milk Production in Dairy Sheep: A Multivariate Study.

Nikolaos Tsekouras, Mathis A B Christodoulopoulos, Eleftherios Meletis, Christos Kousoulis, Polychronis Kostoulas, Vasileios Pantazis, Vasileios G Papatsiros, Konstantina Dimoveli, Dimitrios Gougoulis

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nikolaos TsekourasClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0002-2309-8296
Mathis A B ChristodoulopoulosFaculty of Sciences, Aix-Marseille University, 13007 Marseille, France.ORCID 0009-0007-0240-6417
Eleftherios MeletisFaculty of Public and Integrated Health, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0003-2862-7182
Christos KousoulisAgricultural Cooperative of Cow and Sheep Farmers of Western Thessaly, Lazarina, 43060 Karditsa, Greece.ORCID 0009-0000-1740-0527
Polychronis KostoulasFaculty of Public and Integrated Health, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0001-7051-1541
Vasileios PantazisBiochemistry and Biotechnology Department, University of Thessaly, 41500 Larissa, Greece.
Vasileios G PapatsirosClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0003-4955-0460
Konstantina DimoveliClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.ORCID 0009-0006-2370-8900
Dimitrios GougoulisClinic of Medicine, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0001-9229-3151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examines the use of analgesic medications among sheep farmers, highlighting both their benefits and the significant gaps in their adoption. Our findings indicate that 26.7% of sheep farmers did not utilize any analgesics, a figure that contrasts sharply with high usage rates among swine (over 80%) and cattle (over 85%) farmers. The low utilization of NSAIDs and corticosteroids in sheep farming may be attributed to inadequate education and the lack of approved indications for these medications in Greece. Additionally, we found a positive correlation between farm size and the use of NSAIDs, with larger farms using more NSAIDs, especially flunixin. Furthermore, farms with higher NSAID use-typically the larger ones-tended to have higher milk yields, suggesting that enhanced management practices may contribute to improved outcomes. The results underscore the need for targeted educational initiatives to improve the use of analgesics in sheep farming and address welfare concerns. Overall, this research highlights the importance of addressing gaps in pain management practices in the sheep farming sector to promote better animal welfare. However, further studies with larger sample sizes are needed to expand our understanding of analgesic use and its implications for sheep welfare.

Indexed as

corticosteroids (SAIDs)flunixin megluminemeloxicammilk yieldnon-steroidal anti-inflammatory drugs (NSAIDs)pain managementsheepwelfare assessment

Identifiers

PMID40281937
PMCPMC12023997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.