Evidence map›Paper›PMID 40281865›Full record

ReviewHealthcare (Basel, Switzerland)2025

Dynapenic Abdominal Obesity and Adverse Health Effects in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis.

Li-Kuo Liu, Yu-Chen Su, Hsiao-Chi Tsai, Shu-Fang Chang

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li-Kuo LiuDepartment of Family Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Shilin District, Taipei City 111, Taiwan.ORCID 0000-0003-2334-348X
Yu-Chen SuNursing Department, Hsin Sheng Junior College of Medical Care and Management, Longtan District, Taoyuan City 325, Taiwan.
Hsiao-Chi TsaiCardinal Tien Hospital, Xindian District, New Taipei City 231, Taiwan.
Shu-Fang ChangSchool of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, Beitou District, Taipei City 112, Taiwan.ORCID 0000-0002-1722-1905

Funding

Shin Kong Wu Ho-Su Memorial Hospital 112D007-5 and 113D004-1the National Science and Technology Council MOST 111-2314-B-227-003, NSTC 112-2314-B-227-004, and NSTC 113-2314-B-227-009
6 · The paper itself

Abstract

BACKGROUND/

objectivesDynapenic abdominal obesity is characterized by reduced muscle strength and abdominal fat accumulation and is associated with adverse health outcomes in older adults. Evidence from multiple studies conducted in different countries regarding these outcomes is inconsistent. This systematic review and meta-analysis evaluated the association between dynapenic abdominal obesity and adverse health outcomes-specifically falls, disability, and mortality-among middle-aged and older adults.

methodsA comprehensive search of Embase, PubMed, MEDLINE, CINAHL, and the Cochrane Library (from inception to December 2024) identified 12 eligible prospective cohort studies. Keywords included "older adults", "elderly", "older people", "dynapenic abdominal obesity", "fall", "disability", and "mortality". A systematic review and meta-analysis was conducted using random-effects models, with subgroup analyses based on measurement methods and geographic regions.

resultsDynapenic abdominal obesity was significantly associated with increased risks of falls (hazard ratio = 1.82, 95% confidence interval: 1.04-3.17) and mortality (hazard ratio = 1.50, 95% confidence interval: 1.14-1.96). The subgroup analysis results indicated variations in outcomes across measurement criteria and countries. Dynapenic abdominal obesity was not significantly associated with disability risk (odds ratio = 0.92, 95% confidence interval: 0.18-4.54).

conclusionsDynapenic abdominal obesity is associated with significantly increased fall and mortality risks in middle-aged and older adults. These findings underscore the need for targeted assessments and intervention strategies for high-risk groups.

Indexed as

disabilitydynapenic abdominal obesityfallmeta-analysismortalitysystematic review

Identifiers

PMID40281865
PMCPMC12027035

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.