Evidence map›Paper›PMID 40281775›Full record

ArticleBioengineering (Basel, Switzerland)2025

ACM-Assessor: An Artificial Intelligence System for Assessing Angle Closure Mechanisms in Ultrasound Biomicroscopy.

Yuyu Cong, Weiyan Jiang, Zehua Dong, Jian Zhu, Yuanhao Yang, Yujin Wang, Qian Deng, Yulin Yan, Jiewen Mao, Xiaoshuo Shi and 6 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuyu CongThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Weiyan JiangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Zehua DongThe Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Jian ZhuThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Yuanhao YangThe Department of Comprehensive Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100144, China.
Yujin WangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.ORCID 0000-0001-9862-0512
Qian DengThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Yulin YanThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Jiewen MaoThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Xiaoshuo ShiThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Jiali PanThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Zixian YangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Yingli WangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Juntao FangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.
Biqing ZhengThe School of Resources and Environmental Sciences, Wuhan University, Wuhan 430061, China.
Yanning YangThe Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430061, China.ORCID 0000-0001-8419-6706

Funding

the Interdisciplinary Innovative Talents Foundation from Renmin Hospital of Wuhan University Grant JCRCZN-2022-007the National Natural Science Foundation of China 82101081the National Natural Science Foundation of China 82371023
6 · The paper itself

Abstract

Primary angle-closure glaucoma (PACG), characterized by angle closure (AC) with insidious and irreversible progression, requires precise assessment of AC mechanisms for accurate diagnosis and treatment. This study developed an artificial intelligence system, ACM-Assessor, to evaluate AC mechanisms in ultrasound biomicroscopy (UBM) images. A dataset of 8482 UBM images from 1160 patients was retrospectively collected. ACM-Assessor comprises models for pixel-to-physical spacing conversion, anterior chamber angle boundary segmentation, and scleral spur localization, along with three binary classification models to assess pupillary block (PB), thick peripheral iris (TPI), and anteriorly located ciliary body (ALCB). The integrated assessment model classifies AC mechanisms into pure PB, pure non-PB, multiple mechanisms (MM), and others. ACM-Assessor's evaluation encompassed external testing (2266 images), human-machine competition and assisting beginners' assessment (an independent test set of 436 images). ACM-Assessor achieved accuracies of 0.924 (PB), 0.925 (TPI), 0.947 (ALCB), and 0.839 (integrated assessment). In man-machine comparisons, the system's accuracy was comparable to experts (

Indexed as

angle closure mechanismsartificial intelligenceprimary angle-closure glaucomaultrasound biomicroscopy

Identifiers

PMID40281775
PMCPMC12025151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.