Pressure-Flow Relation of Porcine Thoracic Duct Segment.

Bhavesh Patel, Xiao Lu, Aashish Ahuja, Jillian N Noblet, Joshua F Krieger, Sean Chambers, Max Itkin, Ghassan S Kassab

Abstract read

In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bhavesh PatelCalifornia Medical Innovations Institute, San Diego, CA 92121, USA.

Xiao LuCalifornia Medical Innovations Institute, San Diego, CA 92121, USA.

Aashish AhujaCalifornia Medical Innovations Institute, San Diego, CA 92121, USA.

Jillian N NobletCook Medical, Bloomington, IN 47402, USA.

Joshua F KriegerCook Medical, Bloomington, IN 47402, USA.

Sean ChambersCook Medical, Bloomington, IN 47402, USA.ORCID 0000-0002-3929-2114

Max ItkinCenter for Lymphatic Disorders, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.

Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, CA 92121, USA.

Funding

3DT NAArmy W81XWH-19-1-0087Cook Medical NA

6 · The paper itself

Abstract

The lymphatic system collects excess fluid and molecules from the interstitial space back into the venous system mainly via the thoracic duct (TD). Despite the importance of the lymphatic flow in health and disease, a validated pressure-flow relation of lymphatic fluid through the TD is lacking in a translational large animal model. The objective of this work was to establish a pressure-flow relationship for a TD segment with one valve in a swine model. Our methodology consisted of using a specialized bench experimental setup to measure the passive forward flow of 0.9% saline through single-valve TD segments (

Indexed as

flow resistancelymphatic valvemathematical modelPoiseuille’s law

Identifiers

PMID40281761

DOI10.3390/bioengineering12040401

PMCPMC12024549

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.