Evidence map›Paper›PMID 40281720›Full record

ArticleBioengineering (Basel, Switzerland)2025

Gradual Temperature Rise in Radiofrequency Ablation: Enhancing Lesion Quality and Safety in Porcine Myocardial Tissue.

Cheol-Min Lee, Jae-Young Seo, Jin-Chang Kim, Min-Ku Chon

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheol-Min LeeDepartment of R&D Center, TAU MEDICL Inc., Busan 50612, Republic of Korea.ORCID 0009-0002-7861-454X
Jae-Young SeoDepartment of Internal Medicine, School of Medicine, Pusan National University, Busan 46241, Republic of Korea.ORCID 0009-0007-7665-0631
Jin-Chang KimDepartment of R&D Center, TAU MEDICL Inc., Busan 50612, Republic of Korea.ORCID 0009-0000-6089-5895
Min-Ku ChonDepartment of Internal Medicine, Pusan National University School of Medicine and Cardiology, Cardiovascular Center and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.ORCID 0000-0003-0183-6996

Funding

Korea Medical Device Development Fund grant funded by the Korean government (Ministry of Science and Information and Communication Technology; Ministry of Trade, Industry, and Energy; Ministry of Health and Welfare; Ministry of Food and Drug Safety) Project Number: KMDF_PR_20200901_0059, 1711194236
6 · The paper itself

Abstract

Radiofrequency ablation (RFA) is a pivotal therapeutic technique for various medical conditions, including cardiovascular disease and oncological conditions such as liver and lung cancer. The energy-controlled mode in RFA procedures allows for uniform energy delivery but is less safe compared to the temperature-controlled mode. Therefore, it is necessary to develop a protocol that ensures safety while efficiently delivering energy in the temperature-controlled mode. In this study, we compared lesion formation using the gradual-temperature-rise mode to the fixed-temperature mode. We evaluated the lesion size, energy, cumulative time efficiency, and procedural safety in both in vitro and in vivo experiments with porcine myocardial tissue. Three experimental groups (n = 6) were compared to assess the effect of gradual-temperature-rise and fixed-temperature ablation modes. Five experimental groups (n = 6) were used to determine the optimal temperature turn-up time. The gradual-temperature-rise mode ablated larger lesions (10.48 ± 0.56 mm) compared to the 75 °C (7.67 ± 0.37 mm) and 85 °C (8.05 ± 0.36 mm) fixed-temperature groups (

Indexed as

gradual temperature riseradiofrequency ablationtemperature-controlledturn-up time

Identifiers

PMID40281720
PMCPMC12025035

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.