Evidence map›Paper›PMID 40281692›Full record

ArticleBioengineering (Basel, Switzerland)2025

Deep Learning-Enhanced Motor Training: A Hybrid VR and Exoskeleton System for Cognitive-Motor Rehabilitation.

Kathya P Acuña Luna, Edgar Rafael Hernandez-Rios, Victor Valencia, Carlos Trenado, Christian Peñaloza

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathya P Acuña LunaMirai Innovation Research Institute, Osaka 559-0034, Japan.ORCID 0009-0000-2987-6557
Edgar Rafael Hernandez-RiosMirai Innovation Research Institute, Osaka 559-0034, Japan.ORCID 0009-0006-6398-0722
Victor ValenciaMirai Innovation Research Institute, Osaka 559-0034, Japan.
Carlos TrenadoInstitute for the Future of Education Europe (IFE), 48014 Bilbao, Spain.
Christian PeñalozaMirai Innovation Research Institute, Osaka 559-0034, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research explored the integration of the real-time machine learning classification of motor imagery data with a brain-machine interface, leveraging prefabricated exoskeletons and an EEG headset integrated with virtual reality (VR). By combining these technologies, the study aimed to develop practical and scalable therapeutic applications for rehabilitation and daily motor training. The project showcased an optimized system designed to assess and train cognitive-motor functions in elderly individuals. Key innovations included a motor imagery EEG acquisition protocol for data classification and a machine learning framework leveraging deep learning with a wavelet packet transform for feature extraction. Comparative analyses were conducted with traditional models such as Support Vector Machines (SVMs), Convolutional Neural Networks (CNNs), and Long Short-Term Memory (LSTM) networks. The performance was further enhanced through a random hyperparameter search, optimizing feature extraction and learning parameters to achieve high classification accuracy (89.23%). A novel VR fishing game was developed to dynamically respond to EEG outputs, enabling the performance of interactive motor imagery tasks in coordination with upper limb exoskeleton arms. While clinical testing is ongoing, the system demonstrates potential for increasing ERD/ERS polarization rates in alpha and beta waves among elderly users after several weeks of training. This integrated approach offers a tangible step forward in creating effective, user-friendly solutions for motor function rehabilitation.

Indexed as

EEGexoskeletonmachine learningmotor imageryvirtual realitywavelet package decompositionWPT

Identifiers

PMID40281692
PMCPMC12024311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.