Evidence map›Paper›PMID 40281604›Full record

ArticleBMC musculoskeletal disorders2025

Prediction of screw loosening by measuring the insertion torque in non-osteoporotic patients: an in vitro study.

Jan Ulrich Jansen, Laura Zengerle, Carsten Hackenbroch, Jens Dreyhaupt, Youping Tao, Hans-Joachim Wilke

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jan Ulrich JansenInstitute of Orthopaedic Research and Biomechanics, Centre for Trauma Research Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany.ORCID http://orcid.org/0009-0007-9033-6569
Laura ZengerleInstitute of Orthopaedic Research and Biomechanics, Centre for Trauma Research Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0001-9666-5485
Carsten HackenbrochDepartment of Radiology, German Armed Forces Hospital Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0002-7736-8458
Jens DreyhauptInstitute for Epidemiology and Medical Biometry, Ulm University, Schwabstraße 13, 89075, Ulm, Germany.ORCID http://orcid.org/0000-0001-8057-161X
Youping TaoInstitute of Orthopaedic Research and Biomechanics, Centre for Trauma Research Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany.ORCID http://orcid.org/0000-0003-4865-4655
Hans-Joachim WilkeInstitute of Orthopaedic Research and Biomechanics, Centre for Trauma Research Ulm, Ulm University Medical Centre, Helmholtzstraße 14, 89081, Ulm, Germany. hans-joachim.wilke@uni-ulm.de.ORCID http://orcid.org/0000-0001-6007-8844

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPedicle screws are commonly used in spinal surgeries, but screw loosening remains a major concern, even in non-osteoporotic patients. Predicting pedicle screw stability via the insertion torque is a controversial topic, mainly studied on osteoporotic cadavers. Whether the insertion torque is suitable for patients with healthy bone mineral density (BMD) remains unknown. The aim was to investigate the influencing factors, namely insertion torque, BMD, screw diameter, length, surface area, volume, screw-in rotations, vertebral level, on the screw loosening stability during distractions and to understand if intra-operative predictions are possible.

methodsNon-osteoporotic thoraco-lumbar vertebrae (n = 50) were used to implant five different pedicle screws (n = 100) while measuring the insertion torque. After embedding the endplates, the force needed to distract the screw head by 1 mm was tested.

resultsThe insertion toque (2.3 ± 0.9 Nm) showed the highest influence on the distraction force (324.8 ± 84.4 N) followed by the screw size and vertebral level. BMD did not show any effects.

conclusionsThe linear correlation of insertion torque and the bending force suggests an alternative prediction metric for screw loosening which could improve the outcome of surgeries and patients' safety. This is potentially a simple, intra-operative method, which can be used in future.

Indexed as

Lumbar VertebraePedicle ScrewsProsthesis FailureSpinal FusionThoracic VertebraeTorqueAgedBone DensityFemaleHumansMaleMiddle AgedBiomechanicsDistractionInsertion torquePedicle screwScoliosisScrew loosening

Identifiers

PMID40281604
PMCPMC12023477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.