Evidence map›Paper›PMID 40281572›Full record

ArticleHead & face medicine2025

Tinnitus in patients with orofacial complaints.

Nicole Peter, Jasmine Serventi, Patrick Neff, Dominik Ettlin, Aleksandra Zumbrunn Wojczyńska, Tobias Kleinjung, Nenad Lukic

Abstract read
In one paragraph

Article in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Nicole PeterDepartment of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland. nicole.peter-siegrist@usz.ch.
Jasmine ServentiDepartment of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Patrick NeffDepartment of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Dominik EttlinCenter of Dental Medicine, University of Zurich, Zurich, Switzerland.
Aleksandra Zumbrunn WojczyńskaOrofacial Pain Unit, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Tobias Kleinjung *Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland. tobias.kleinjung@usz.ch.
Nenad Lukic *Orofacial Pain Unit, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explored subjective tinnitus frequency in patients referred to an interdisciplinary orofacial pain clinic using the "web-based interdisciplinary symptom evaluation" (WISE) tool, which included a wide range of psychometric data. Our goal was to analyze the correlation between orofacial complaints and tinnitus, as well as their association with other psychometric data-an approach that, to our knowledge, has not been undertaken to this extent before.

methodsFrom 2017 to 2020, we analyzed 1369 anonymized patient records using completed WISE. This included diverse questionnaires and symptom-related screener questions. Positive screening responses triggered additional assessments, such as short Tinnitus Handicap Inventory (THI-12) and Patient Health Questionnaire 4 (PHQ-4). Ear symptoms, tinnitus severity and tinnitus frequency were evaluated. Furthermore, Spearman correlations were performed with other questionnaires addressing pain, anxiety, depression, health, stress and insomnia.

resultsAmong 1369 patients with orofacial complaints, 69% were female. Notably, 19.7% (269) completed THI-12 due to severe ear symptoms; of these, 62.1% were female. Female mean THI-12 score was significantly lower (p = 0.007) with 9.3 (SD = 7.0) compared to males 11.6 (SD = 6.8). Additionally, there was a significantly different gender distribution between all patients with tinnitus and those with severe tinnitus (p = 0.032), with an increased proportion of men in the latter group. THI-12 positively correlated with all WISE questionnaires, strongest with PHQ-4 (p < 0.01).

conclusionsOur study unveils a common co-occurrence of orofacial and ear complaints, particularly tinnitus. The practical implication of the observed gender differences suggests that in male patients presenting with orofacial pain, tinnitus and its associated distress should be actively addressed to initiate a multidisciplinary treatment approach. CLINICAL TRIAL NUMBER: Not applicable. Since this study was a retrospective analysis of anonymized data, trial registration was not necessary.

Indexed as

Facial PainTinnitusAdultAgedFemaleHumansMaleMiddle AgedPsychometricsSeverity of Illness IndexSurveys and QuestionnairesOrofacial complaintSomatosensory tinnitusTemporomandibular dysfunctionTinnitusTMDWeb-based interdisciplinary symptom evaluationWISE

Identifiers

PMID40281572
PMCPMC12032725

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.