Evidence map›Paper›PMID 40281539›Full record

ArticleBMC public health2025

Sexually transmitted infections in the non-European Union and European Economic Area of the World Health Organization European Region 2021-2023.

Machiko Otani, Jane Rowley, Viatcheslav Grankov, Giorgi Kuchukhidze, Stela Bivol, WHO European Region non-EU/EEA STI Surveillance network

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Machiko OtaniWorld Health Organization Regional Office for Europe, Copenhagen, Denmark. otanim@who.int.
Jane RowleyDepartment of Global HIV, Hepatitis and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland.
Viatcheslav GrankovWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
Giorgi KuchukhidzeWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
Stela BivolWorld Health Organization Regional Office for Europe, Copenhagen, Denmark.
WHO European Region non-EU/EEA STI Surveillance network

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs) continue to be a significant public health challenge and have an impact on sexual and reproductive health. European Union and European Economic Area (EU/EEA) countries report data annually on the number of cases of syphilis, gonorrhoea, chlamydia, and lymphogranuloma venereum (LGV) to the European Centre for Disease Prevention and Control. No similar system exists for the non-EU/EEA countries in the WHO European Region, and therefore, the sub-regional overview was unclear due to the limited data availability and inconsistency.

methodsWe conducted a survey among 24 WHO member states in the WHO European Region that did not belong to the EU/EEA as of June 2024. The survey collected data on STI surveillance systems and numbers of reported cases of syphilis, gonorrhoea, chlamydia and LGV from 2021 to 2023.

resultsTwenty-one completed the survey, of which 19 (79%) agreed to publish their data. All 19 countries reported surveillance activities for syphilis, 18 for gonorrhoea and chlamydia, and 8 for LGV. The comprehensiveness and coverage of surveillance systems varied between countries and infections. Total cases reported increased from 13,553 to 17,113 (notification rate per 100,000 population 5.4 to 6.9) for syphilis and 12,001 to 13,067 (4.2 to 5.0) for gonorrhoea between 2021 and 2023, while chlamydia cases decreased from 32,556 to 27,802 (13.3 to 11.2). Only one to two LGV cases were reported per year. Various challenges were identified in antimicrobial-resistant gonorrhoea surveillance.

conclusionsIn non-EU/EEA countries, STI cases are likely to be underreported due to incomplete surveillance systems and other factors. Given the increase in the number of reported cases of syphilis and gonorrhoea between 2021 and 2023 and the significant public health consequences of untreated STIs, an accelerated joint effort to strengthen the surveillance systems of the non-EU/EEA countries is warranted to move towards ending epidemics of STIs in the WHO European Region by 2030.

Indexed as

Sexually Transmitted DiseasesEuropeEuropean UnionFemaleGonorrheaHumansMalePopulation SurveillanceSurveys and QuestionnairesSyphilisWorld Health OrganizationCentral AsiaChlamydiaEuropeGonorrhoeaLymphogranuloma venereumSexually transmitted infectionSyphilis

Identifiers

PMID40281539
PMCPMC12023690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.