Bilateral total knee replacement for hemophilic arthropathy: a case report.

Mahmoud A Hafez, Mohamed Talaat, Ahmad Yaman Kebbe, Abdelrahman Helmy, Abdelrahman M Makram

Abstract readCase Reports

In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Mahmoud A HafezThe Orthopaedic Department, Faculty of Medicine, October 6 University, Giza, Egypt. mhafez@msn.com.ORCID http://orcid.org/0000-0002-6285-5720

Mohamed TalaatDepartment of Hematology, Faculty of Medicine, October 6 University, Giza, Egypt.

Ahmad Yaman KebbeThe Orthopaedic Department, Faculty of Medicine, October 6 University, Giza, Egypt.ORCID http://orcid.org/0009-0002-6416-0022

Abdelrahman HelmyThe Orthopaedic Department, Faculty of Medicine, October 6 University, Giza, Egypt.

Abdelrahman M MakramThe Orthopaedic Department, Faculty of Medicine, October 6 University, Giza, Egypt.ORCID http://orcid.org/0000-0003-2011-8092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Von Willebrand disease (vWD) and hemophilia present unique challenges in orthopedic surgery due to their inherent bleeding risks and potential complications. While joint bleedings are well-documented in hemophilia, they are less understood in vWD, especially regarding their impact on daily activities and the development of arthropathy. We present a case of a young female patient aged 25 years with vWD Type 3 who underwent bilateral total knee replacement (TKR) due to end-stage knee osteoarthritis. Following two previous operations of the right knee at the age of 14, the patient had high degree of extra-articular valgus and intra-articular deformity, ankylosed knee in 30

Indexed as

Arthroplasty, Replacement, KneeHemophilia AKnee JointOsteoarthritis, Kneevon Willebrand DiseasesAdultFemaleHumansTreatment OutcomeFused knee arthroplastyPatient-specific templatingTotal knee replacementValgus deformityVon Willebrand disease

Identifiers

PMID40281505

DOI10.1186/s12891-025-08611-1

PMCPMC12023443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.