Evidence map›Paper›PMID 40281457›Full record

ArticleBMC public health2025

Disparities in cigarette smoking and the health of marginalized populations in the U.S.: a simulation analysis.

Douglas E Levy, Stephanie S Lee, Yiqi Qian, Fatma M Shebl, Sydney L Goldberg, Nora M Mulroy, Nicola K Anderson, Emily P Hyle, Jessica E Becker, Krishna P Reddy

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Unmet Health-Related Social Needs Among Black Adults Who Smoke.Journal of racial and ethnic health disparities · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Douglas E LevyMongan Institute Health Policy Research Center, Massachusetts General Hospital, Boston, MA, USA. dlevy3@mgh.harvard.edu.
Stephanie S LeeMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Yiqi QianMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Fatma M SheblHarvard Medical School, Boston, MA, USA.
Sydney L GoldbergMongan Institute Health Policy Research Center, Massachusetts General Hospital, Boston, MA, USA.
Nora M MulroyMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Nicola K AndersonMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Emily P HyleHarvard Medical School, Boston, MA, USA.
Jessica E BeckerDepartment of Child and Adolescent Psychiatry, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.
Krishna P ReddyTobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, USA.

Funding

Reducing Environmental Tobacco Smoke Exposure in Public HousingR01HL112212 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LEVY, DOUGLAS · 2012 to 2020
$5.0M
The Impact of Hearing Loss Treatment Scale-Up in Persons Aging with HIV on Dementia Risk, Quality of Life, and Healthcare CostsR01AG069575 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYLE, EMILY PARKER · 2021 to 2025
$4.6M
Assessing the impact of vaping control policies at the school, local and state levelsR01DA054935 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Douglas Levy · 2022 to 2026
$3.8M
Tobacco Use and Cessation, HIV, and TB in South Africa: Clinical and Economic Outcomes (Clinical and public health approaches to tobacco cessation in South Africa supplement)R01DA050482 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI REDDY, KRISHNA P · 2020 to 2024
$3.4M
Clinical and Economic Outcomes of HIV, Cigarette Smoking, and Smoking Cessation InterventionsK01DA042687 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI REDDY, KRISHNA P · 2016 to 2020
$929k
AHRQ HHS T32 HS000063AHRQ HHS T32-HS000063American Academy of Child and Adolescent Psychiatry Junior Investigator AwardAmerican Lung Association IA-834584NHLBI NIH HHS R01 HL112212NHLBI NIH HHS R01-HL112212NIA NIH HHS R01 AG069575NIA NIH HHS R01-AG069575NIDA NIH HHS K01 DA042687NIDA NIH HHS K01-DA042687NIDA NIH HHS R01 DA050482NIDA NIH HHS R01 DA054935NIDA NIH HHS R01-DA054935
6 · The paper itself

Abstract

introductionPeople with low socioeconomic status (SES) or serious psychological distress (SPD) in the U.S. face ongoing and future disparities in tobacco smoking. We sought to estimate how smoking disparities contribute to disparities in life expectancy and aggregate life-years in these marginalized subpopulations.

methodsWe used the Simulation of Tobacco and Nicotine Outcomes and Policy (STOP) microsimulation model to project life expectancy as a function of subpopulation (low SES, higher SES, SPD, or non-SPD) and cigarette smoking status. Low SES was defined as having at least one of the following: income below poverty, less than high school education, or Medicaid insurance. Higher SES individuals belonged to none of these categories. SPD was defined as Kessler-6 score ≥ 13; non-SPD was a Kessler-6 score < 13. To project individual life expectancy losses from smoking, we simulated 40-year-olds stratified by gender, subpopulation (by SES or by SPD, with no change), and smoking status (current/never, with no change). To project time to reach 5% cigarette smoking prevalence (U.S.) - reflecting one tobacco "endgame" threshold - in each subpopulation, we simulated the entire subpopulations of people with low SES, higher SES, SPD, and non-SPD, incorporating corresponding distributions of gender, age, and smoking status and accounting for changes in smoking behaviors and secular smoking trends. We then estimated total life-years accumulated under status quo and alternate scenarios in which smoking dynamics in the marginalized subpopulations matched those of their less marginalized counterparts.

resultsThe model showed that, for individuals with low SES or SPD, smoking is associated with substantial loss of life expectancy (9.8-11.5y). Marginalized subpopulations would reach 5% smoking prevalence 20y (low SES) and 17y (SPD) sooner if smoking trends mirrored their less marginalized counterparts; these differences result in 5.3 million (low SES) and 966,000 (SPD) excess life-years lost over 40y.

conclusionsDifferences in cigarette smoking portend substantial ongoing and future disparities in life expectancy and time to reach 5% smoking prevalence. Reducing tobacco-related disparities in the U.S. will require an explicitly equity-focused vision, and the tobacco endgame will only be truly achieved when it includes all groups.

Indexed as

Cigarette SmokingHealth Status DisparitiesAdultComputer SimulationFemaleHumansLife ExpectancyMaleMiddle AgedSocial ClassUnited StatesHealth disparitiesSimulation modelingTobacco

Identifiers

PMID40281457
PMCPMC12023394

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.